Evidence map›Paper›PMID 32103630›Full record

Observational studyArthritis & rheumatology (Hoboken, N.J.)2020

Physician Prescribing Patterns and Risk of Future Long-Term Opioid Use Among Patients With Rheumatoid Arthritis: A Prospective Observational Cohort Study.

Yvonne C Lee, Bing Lu, Hongshu Guan, Jeffrey D Greenberg, Joel Kremer, Daniel H Solomon

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Arthritis & rheumatology (Hoboken, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Towards an individualised approach to pain management in inflammatory arthritis.Therapeutic advances in musculoskeletal disease · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yvonne C LeeNorthwestern University Feinberg School of Medicine, Chicago, Illinois, and Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0002-2105-3393
Bing LuBrigham and Women's Hospital, Boston, Massachusetts.
Hongshu GuanBrigham and Women's Hospital, Boston, Massachusetts.
Jeffrey D GreenbergCorrona, LLC, Waltham, Massachusetts, and New York University, New York, New York.
Joel KremerCorrona, LLC, Waltham, Massachusetts, and Albany Medical College, Albany, New York.
Daniel H SolomonBrigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0001-8202-5428
Brigham and Women's Hospital · USAlbany Medical Center Hospital · USEducation Development Center · USNorthwestern University · US

Funding

VERITY: Value and Evidence in Rheumatology using bioInformaTics, and advanced analYticsP30AR072577 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Daniel Hal Solomon · 2017 to 2026
$9.8M
Dietary Quality, Body Adiposity, and Risk of Rheumatoid Arthritis in WomenR01AR071326 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI LU, BING, SOLOMON, DANIEL HAL · 2018 to 2021
$1.8M
NIAMS NIH HHS P30 AR072577NIAMS NIH HHS R01 AR071326
6 · The paper itself

Abstract

objectiveTo identify the extent to which opioid prescribing rates for patients with rheumatoid arthritis (RA) vary in the US and to determine the implications of baseline opioid prescribing rates on the probability of future long-term opioid use.

methodsWe identified patients with RA from physicians who contributed ≥10 patients within the first 12 months of participation in the Corrona RA Registry. The baseline opioid prescribing rate was calculated by dividing the number of patients with RA reporting opioid use during the first 12 months by the number of patients with RA providing data that year. To estimate odds ratios (ORs) for long-term opioid use, we used generalized linear mixed models.

resultsDuring the follow-up period, long-term opioid use was reported by 7.0% (163 of 2,322) of patients of physicians with a very low rate of opioid prescribing (referent) compared to 6.8% (153 of 2,254) of patients of physicians with a low prescribing rate, 12.5% (294 of 2,352) of patients of physicians with a moderate prescribing rate, and 12.7% (307 of 2,409) of patients of physicians with a high prescribing rate. The OR for long-term opioid use after the baseline period was 1.16 (95% confidence interval [95% CI] 0.79-1.70) for patients of low-intensity prescribing physicians, 1.89 (95% CI 1.27-2.82) for patients of moderate-intensity prescribing physicians, and 2.01 (95% CI 1.43-2.83) for patients of high-intensity prescribing physicians, compared to very low-intensity prescribing physicians.

conclusionRates of opioid prescriptions vary widely. Our findings indicate that baseline opioid prescribing rates are a strong predictor of whether a patient will become a long-term opioid user in the future, after controlling for patient characteristics.

Indexed as

Duration of TherapyAdultAgedAnalgesics, OpioidArthralgiaArthritis, RheumatoidCohort StudiesFemaleHumansLinear ModelsMaleMiddle AgedOdds RatioPractice Patterns, Physicians'Prospective StudiesAnalgesics, Opioid

Identifiers

PMID32103630
PMCPMC7329590
OpenAlexW3008503893

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.