Evidence map›Paper›PMID 32103603›Full record

Trial reportInternational wound journal2020

A pilot multi-centre prospective randomised controlled trial of RECELL for the treatment of venous leg ulcers.

Paul D Hayes, Keith G Harding, Susan M Johnson, Charles McCollum, Luc Téot, Kevin Mercer, David Russell

Abstract readCase ReportsMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in International wound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Trial
  3. What's New in Wound Healing: Treatment Advances and Microbial Insights.American journal of clinical dermatology · 2025
    Review
  4. Article
  5. Article
  6. A single institution case series of ReCellInternational journal of burns and trauma · 2023
    Article
  7. Allogeneic ABCB5JID innovations : skin science from molecules to population health · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paul D HayesSt John's Innovation Centre, Cambridge, UK.
Keith G HardingClinical Innovation Cardiff, Cardiff, Wales.
Susan M JohnsonDoncaster Royal Infirmary, Doncaster, UK.
Charles McCollumWythenshawe Hospital, Manchester, UK.
Luc TéotLapeyronie Health Facility, Montpellier, France.
Kevin MercerBradford Royal Infirmary, Bradford, UK.
David RussellLeeds General Infirmary, Leeds, UK.

Funding

AVITA Medical
6 · The paper itself

Abstract

Venous leg ulcers (VLUs) have a significant impact on approximately 3% of the adult population worldwide, with a mean NHS wound care cost of £7600 per VLU over 12 months. The standard care for VLUs is compression therapy, with a significant number of ulcers failing to heal with this treatment, especially with wound size being a risk factor for non-healing. This multicentre, prospective, randomised trial evaluated the safety and effectiveness of autologous skin cell suspension (ASCS) combined with compression therapy compared with standard compression alone (Control) for the treatment of VLUs. Incidence of complete wound closure at 14 weeks, donor site closure, pain, Health-Related Quality of Life (HRQoL), satisfaction, and safety were assessed in 52 patients. At Week 14, VLUs treated with ASCS + compression had a statistically greater decrease in ulcer area compared with the Control (8.94 cm

Indexed as

AgedAged, 80 and overCell TransplantationCompression BandagesFemaleFibroblastsHumansKeratinocytesMaleMelanocytesMiddle AgedPatient SatisfactionPilot ProjectsProspective StudiesSkin TransplantationTransplantation, Autologousautologous skin cell suspensioncompression therapyhealth-related quality of lifeRECELLvenous leg ulcers

Identifiers

PMID32103603
PMCPMC7217204

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.