Evidence map›Paper›PMID 32103425›Full record

ReviewIndian journal of pediatrics2020

Multi-Drug Resistant and Extensively-Drug Resistant Tuberculosis.

Ira Shah, Vishrutha Poojari, Himali Meshram

Abstract readReview
PubMed Publisher
In one paragraph

Review in Indian journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Infectious Diseases in Children, Never a Dull Moment!Indian journal of pediatrics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ira ShahPediatric TB and DR-TB Clinic, Department of Pediatric Infectious Diseases, B J Wadia Hospital for Children, Mumbai, 400012, India. irashah@pediatriconcall.com.
Vishrutha PoojariPediatric TB and DR-TB Clinic, Department of Pediatric Infectious Diseases, B J Wadia Hospital for Children, Mumbai, 400012, India.
Himali MeshramPediatric TB and DR-TB Clinic, Department of Pediatric Infectious Diseases, B J Wadia Hospital for Children, Mumbai, 400012, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

India is one of the high burden countries for tuberculosis (TB) including multi-drug resistant TB (MDR-TB) and extensively-drug resistant (XDR) TB. Drug-resistant (DR) TB has threatened the TB care and is a major health problem in many countries; treatment of DR TB has been difficult requiring use of reserve or second-line drugs, cost factors, has extensive side-effect profile and long duration of treatment. Treatment in MDR-TB are increasingly becoming individualised mainly due to preference for oral over injectable, results of drug susceptibility testing (DST), population resistance levels, history of previous TB treatment, drug tolerability and drug-to-drug interactions. Bedaquilline (BDQ) and delaminid (DLM) are new drugs available for treatment of these patients. World Health Organization (WHO) recommends use of BDQ in more than 15 y (>15 kg) patients only. Under Revised National Tuberculosis Control Programme (RNTCP) the use of this drug is recommended for patients older than 18 y only. Under RNTCP, the use of DLM is approved in children 6 y and above. Pediatric MDR/XDR TB treatment outcome with newer anti-TB drugs and regimen is lacking. Children when treated with individualized regimens have improved survival.

Indexed as

Extensively Drug-Resistant TuberculosisMycobacterium tuberculosisPharmaceutical PreparationsTuberculosis, Multidrug-ResistantAntitubercular AgentsChildHumansIndiaMicrobial Sensitivity TestsAntitubercular AgentsPharmaceutical PreparationsChildrenExtensively-drug resistant TB (XDR-TB)IndiaMultidrug resistant TB (MDR-TB)TreatmentTuberculosis (TB)

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.