ArticleEuropean radiology2020
Comparison of whole-body MRI with diffusion-weighted imaging and PET/CT in lymphoma staging.
Article in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Diagnostic accuracy of 18F-FDG PET/CT scan in distant metastasis staging of non-small cell lung cancer: A meta-analysis.Medicine · 2026Pooled it
- Differentiating malignant from benign splenic lesions: a meta-analysis and pictorial review of imaging features.Abdominal radiology (New York) · 2024Pooled it
- Radiological Approach to Splenomegaly: Etiologies, Pathophysiologies, and Diagnostic Strategies.Korean journal of radiology · 2026Review
- Comparing Whole-Body Diffusion-weighted MRI to Conventional Imaging: Staging Pediatric Bone and Soft-Tissue Sarcomas.Radiology. Imaging cancer · 2025Article
- [Primary imaging diagnostics of lymphomas].Radiologie (Heidelberg, Germany) · 2025Review
- Liquid Biopsy in B and T Cell Lymphomas: From Bench to Bedside.International journal of molecular sciences · 2025Review
- A Radiation-Free Approach Based on the Whole-Body MRI Has Shown a High Level of Accuracy in the Follow-Up of Lymphoma Patients-A Single Center Retrospective Study.Journal of clinical medicine · 2024Article
- Diagnostic performance of different imaging modalities for splenic malignancies: A comparative meta-analysis.European journal of radiology open · 2024Article
- Intravoxel incoherent motion diffusion-weighted MRI for the evaluation of early spleen involvement in acute leukemia.Quantitative imaging in medicine and surgery · 2024Article
- [European radiology · 2023Article
- Whole body MRI with Diffusion Weighted Imaging versus 18F-fluorodeoxyglucose-PET/CT in the staging of lymphomas.La Radiologia medica · 2023Article
- Comparison of whole-body DW-MRI with 2-[European journal of nuclear medicine and molecular imaging · 2023Article
- Technical Advancements in Abdominal Diffusion-weighted Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023Review
- Whole‑body MRI for metastatic workup in patients diagnosed with cancer.Molecular and clinical oncology · 2023Article
- Whole-body diffusion-weighted imaging with background body signal suppression and quantitative apparent diffusion coefficient in the detection, staging, and grading of non-Hodgkin lymphoma.Polish journal of radiology · 2023Article
- Diagnostic performance of integrated whole-bodyFrontiers in oncology · 2023Article
- Diagnostic Accuracy of 2-[European radiology · 2022Article
- The diagnostic performance of whole-body MRI in the staging of lymphomas in adult patients compared to PET/CT and enhanced reference standard-systematic review and meta-analysis.Quantitative imaging in medicine and surgery · 2022Article
- The Diagnostic Value ofContrast media & molecular imaging · 2022Article
- Whole-body diffusion-weighted MRI of normal lymph nodes: prospective apparent diffusion coefficient histogram and nodal distribution analysis in a healthy cohort.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021Article
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5 authors at 1 institution in 1 country.
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Abstract
objectivesTo compare the diagnostic efficiency of whole-body MRI-DWI and PET/CT in lymphoma staging.
methodsA prospective study enrolled 92 patients with lymphoma. Prior to treatment, all patients underwent whole-body MRI-DWI and PET-CT. The methods' efficiency was compared in the diagnosis of lymph node (LN) and organ involvement, and in determining lymphoma stage.
resultsSensitivity, specificity, and accuracy in the diagnosis of enlarged LN involvement were 98.2%, 99.9%, and 99.3%, respectively, for MRI-DWI, and 99.4%, 100.0%, and 99.8%, respectively, for PET/CT. ROC analysis showed similar methods' efficiency in the diagnosis of enlarged LN involvement (p > 0.06). MRI-DWI and PET/CT sensitivity in the diagnosis of non-enlarged LN involvement was 77.8% and 88.1%, respectively (p < 0.001). MRI-DWI and PET/CT sensitivity, specificity, and accuracy in the diagnosis of lung involvement were 73.3%, 98.7%, 94.6% and 86.7%, 98.7%, 96.7%; spleen involvement 54.8%, 98.3%, 83.3% and 100.0%, 100.0%, 100.0%; bone marrow involvement 87.1%, 96.4%, 93.0% and 64.5%, 87.3%, 79.1%; and all-organ involvement 72.9%, 98.1%, 91.4% and 80.0%, 96.6%, 92.2%, respectively. ROC analysis showed similar methods' efficiency in the diagnosis of lung involvement (р > 0.3), higher for PET/CT in spleen involvement (р < 0.0001), higher for MRI-DWI in bone marrow involvement (р < 0.0008), and similar in all-organ involvement (р > 0.35). MRI-DWI and PET/CT determined the correct lymphoma stage in 79 (86%) patients.
conclusionsWhole-body MRI-DWI and PET/CT determined the correct lymphoma stage in similar numbers of patients. MRI-DWI can serve as a non-irradiative alternative to PET/CT in lymphoma staging. KEY POINTS: • Whole-body MRI-DWI efficiency compared with that of PET/CT is similar in the diagnosis of enlarged LN involvement, inferior in the diagnosis of non-enlarged LN and spleen involvement, but superior in the diagnosis of bone marrow involvement. • A new efficient MRI-DWI sign for diagnosis of diffuse bone marrow involvement has been proposed, i.e., a diffuse increase in spine signal intensity on high b value DWI images above the kidney parenchyma. • MRI-DWI and PET/CT determined the correct lymphoma stage in similar numbers of patients.
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