Evidence map›Paper›PMID 32103362›Full record

ArticleJournal of ophthalmic inflammation and infection2020

Acute macular neuroretinopathy with coexistent central retinal vein occlusion as the presenting feature in intraocular tuberculosis.

Ramesh Venkatesh, Sajjan Sangai, Arpitha Pereira, Padmamalini Mahendradas, Naresh Kumar Yadav

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmic inflammation and infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ramesh VenkateshDepartment of Retina, Vitreous and Ocular Inflammation, Narayana Nethralaya, #121/C, 1st R block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India. vramesh80@yahoo.com.ORCID http://orcid.org/0000-0002-4479-9390
Sajjan SangaiDepartment of Retina, Vitreous and Ocular Inflammation, Narayana Nethralaya, #121/C, 1st R block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India.
Arpitha PereiraDepartment of Retina, Vitreous and Ocular Inflammation, Narayana Nethralaya, #121/C, 1st R block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India.
Padmamalini MahendradasDepartment of Retina, Vitreous and Ocular Inflammation, Narayana Nethralaya, #121/C, 1st R block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India.
Naresh Kumar YadavDepartment of Retina, Vitreous and Ocular Inflammation, Narayana Nethralaya, #121/C, 1st R block, Chord Road, Rajaji Nagar, Bengaluru, 560010, India.
Narayana Nethralaya · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo report a case of intraocular tuberculosis presenting as acute macular neuroretinopathy and central retinal vein occlusion. CASE DESCRIPTION: A 29-year-old man presented to the retina clinic with complaints of sudden blurring of vision in the left eye of 3 days duration. His visual acuity was 6/6 and 6/18 in the right and left eye, respectively. Fundus examination of the left eye showed features of central retinal vein occlusion. OCT showed features of type 2 acute macular neuroretinopathy (AMN) as well. Over a period of 2 weeks, the patient developed choroidal granulomas with overlying retinal elevation and peripapillary choroidal neovascular membrane and retinal granuloma. Mantoux test and HRCT chest confirmed the diagnosis of pulmonary tuberculosis.

resultsThe patient was treated with a course of antitubercular therapy, oral corticosteroids and a single dose of intravitreal anti-vascular endothelial growth factor (1.25 mg/0.05 ml Bevacizumab, Roche Pharma) injection. After 6 months of therapy with ATT and tapering course of oral steroids, there was a complete resolution of all clinical signs including the choroidal granuloma with an improvement in visual acuity to 6/6.

conclusionAcute macular neuroretinopathy can complicate intraocular TB. Tuberculosis should be kept as one of the differential diagnosis in patients with AMN. Prognosis is generally good in patients of ocular TB presenting with retinal vascular occlusions.

Indexed as

Acute macular neuroretinopathyCentral retinal vein occlusionIntraocular tuberculosis

Identifiers

PMID32103362
PMCPMC7044390
OpenAlexW3011597665

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.