Evidence map›Paper›PMID 32103321›Full record

ArticleHeart and vessels2020

Prognostic implication of global myocardial blood flow in patients with ST-segment elevation myocardial infarction.

Rikuta Hamaya, Yoshihisa Kanaji, Masahiro Hada, Yoshinori Kanno, Eisuke Usui, Masahiro Hoshino, Masao Yamaguchi, Yohei Sumino, Tomoki Horie, Hidenori Hirano and 2 more

Abstract read
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In one paragraph

Article in Heart and vessels, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rikuta HamayaDepartment of Cardiology, Tsuchiura Kyodo General Hospital, 4-4-1 Otsuno, Tsuchiura, Ibaraki, 300-0028, Japan.
Yoshihisa KanajiDepartment of Cardiology, Tsuchiura Kyodo General Hospital, 4-4-1 Otsuno, Tsuchiura, Ibaraki, 300-0028, Japan.
Masahiro HadaDepartment of Cardiology, Tsuchiura Kyodo General Hospital, 4-4-1 Otsuno, Tsuchiura, Ibaraki, 300-0028, Japan.
Yoshinori KannoDepartment of Cardiology, Tsuchiura Kyodo General Hospital, 4-4-1 Otsuno, Tsuchiura, Ibaraki, 300-0028, Japan.
Eisuke UsuiDepartment of Cardiology, Tsuchiura Kyodo General Hospital, 4-4-1 Otsuno, Tsuchiura, Ibaraki, 300-0028, Japan.
Masahiro HoshinoDepartment of Cardiology, Tsuchiura Kyodo General Hospital, 4-4-1 Otsuno, Tsuchiura, Ibaraki, 300-0028, Japan.
Masao YamaguchiDepartment of Cardiology, Tsuchiura Kyodo General Hospital, 4-4-1 Otsuno, Tsuchiura, Ibaraki, 300-0028, Japan.
Yohei SuminoDepartment of Cardiology, Tsuchiura Kyodo General Hospital, 4-4-1 Otsuno, Tsuchiura, Ibaraki, 300-0028, Japan.
Tomoki HorieDepartment of Cardiology, Tsuchiura Kyodo General Hospital, 4-4-1 Otsuno, Tsuchiura, Ibaraki, 300-0028, Japan.
Hidenori HiranoDepartment of Cardiology, Tsuchiura Kyodo General Hospital, 4-4-1 Otsuno, Tsuchiura, Ibaraki, 300-0028, Japan.
Tomoyo SugiyamaDepartment of Cardiology, Tsuchiura Kyodo General Hospital, 4-4-1 Otsuno, Tsuchiura, Ibaraki, 300-0028, Japan.
Tsunekazu KakutaDepartment of Cardiology, Tsuchiura Kyodo General Hospital, 4-4-1 Otsuno, Tsuchiura, Ibaraki, 300-0028, Japan. kaz@joy.email.ne.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognostic implications of cardiovascular magnetic resonance imaging (CMR)-derived hyperemic myocardial blood flow (MBF) in patients with ST-elevation myocardial infarction (STEMI) are unknown. This study sought to investigate the incremental prognostic value of hyperemic MBF over conventional CMR markers to identify patients with high risk of future incidence of patient-oriented composite outcomes (POCO) and major adverse cardiac events (MACE) after STEMI. A total of 237 patients who presented with STEMI were prospectively enrolled. The CMR protocol included left-ventricular ejection fraction (LVEF), late gadolinium enhancement (LGE) and microvascular obstruction (MVO) measurement, and volumetric MBF assessment. During a median follow-up of 2.6 years, 47 patients experienced POCO (primary outcome) and 21 patients had MACE. In a multivariable model, multivessel disease, LGE, MVO, and hyperemic MBF were independently associated with POCO. Addition of hyperemic MBF to the model consisting of GRACE score, multivessel disease, LVEF, LGE, and MVO significantly improved the predictive efficacy (integrated discrimination improvement 0.020, p = 0.021). Patients with low hyperemic MBF had significantly higher incidence of MACE compared to those with high hyperemic MBF in propensity score matching analysis (p = 0.018). In conclusion, CMR-derived hyperemic MBF could provide independent and incremental prognostic value over LVEF, LGE, and MVO in patients with STEMI.

Indexed as

Coronary CirculationMagnetic Resonance Imaging, CineMyocardial Perfusion ImagingAgedCoronary SinusFemaleHeart Disease Risk FactorsHumansHyperemiaMaleMiddle AgedPercutaneous Coronary InterventionPredictive Value of TestsReproducibility of ResultsRetrospective StudiesRisk AssessmentCardiovascular magnetic resonance imagingCoronary flow reserveMyocardial blood flowST-segment elevation myocardial infarction

Identifiers

PMID32103321

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.