Evidence map›Paper›PMID 32103158›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2020

Estimates of healthcare spending for preterm and low-birthweight infants in a commercially insured population: 2008-2016.

Andrew L Beam, Inbar Fried, Nathan Palmer, Denis Agniel, Gabriel Brat, Kathe Fox, Isaac Kohane, Anna Sinaiko, John A F Zupancic, Joanne Armstrong

Open access · hybridAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 3 pooled it
28.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 3 syntheses or guidelines pooled it, 181 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Incubator baby side-shows: the history and future of neonatology.Proceedings (Baylor University. Medical Center) · 2026
    Article
  8. Article
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  12. The Influence of County Contexts on Preterm Births Among Latina Mothers in the US.Journal of racial and ethnic health disparities · 2026
    Article
  13. Article
  14. Voting Restrictions and Increased Odds of Adverse Birth Outcomes in the US.Journal of racial and ethnic health disparities · 2026
    Article
  15. Article
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  20. Variation in NICU utilization: a narrative review and path forward.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Andrew L BeamDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA. Andrew_Beam@hms.harvard.edu.
Inbar FriedDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Nathan PalmerDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Denis AgnielDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Gabriel BratDepartment of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Kathe FoxDepartment of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Isaac KohaneDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Anna SinaikoDepartment of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
John A F ZupancicDepartment of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA.ORCID http://orcid.org/0000-0003-1734-7193
Joanne ArmstrongDepartment of Women's Health, Aetna Inc, Boston, MA, USA.
Harvard University · USBeth Israel Deaconess Medical Center · USAetna (United States) · USBrigham and Women's Hospital · USUniversity of North Carolina at Chapel Hill · US

Funding

Predicting Pulmonary and Cardiac Morbidity in Preterm Infants with Deep LearningK01HL141771 · NHLBI · HARVARD SCHOOL OF PUBLIC HEALTH · PI BEAM, ANDREW L. · 2019 to 2023
$832k
NHLBI NIH HHS K01 HL141771
6 · The paper itself

Abstract

The growth in healthcare spending is an important topic in the United States, and preterm and low-birthweight infants have some of the highest healthcare expenditures of any patient population. We performed a retrospective cohort study of spending in this population using a large, national claims database of commercially insured individuals. A total of 763,566 infants with insurance coverage through Aetna, Inc. for the first 6 months of post-natal life were included, and received approximately $8.4 billion (2016 USD) in healthcare services. Infants with billing codes indicating preterm status (<37 weeks, n = 50,511) incurred medical expenditures of $76,153 on average, while low-birthweight status (<2500 g) was associated with average spending of $114,437. Infants born at 24 weeks gestation (n = 418) had the highest per infant average expenditures of $603,778. Understanding the drivers of variation in costs within gestational age and birthweight bands is an important target for future studies.

Indexed as

Pregnancy, MultiplePremature BirthBirth WeightFemaleHealth ExpendituresHumansInfantInfant, NewbornInfant, PrematurePregnancyPregnancy OutcomeReproductive Techniques, AssistedRetrospective StudiesUnited States

Identifiers

PMID32103158
PMCPMC7314662
OpenAlexW3006680891

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.