Evidence map›Paper›PMID 32103132›Full record

ArticleScientific reports2020

MitoBlue as a tool to analyze the mitochondria-lysosome communication.

Mateo I Sánchez, Yolanda Vida, Ezequiel Pérez-Inestrosa, José L Mascareñas, M Eugenio Vázquez, Ayumu Sugiura, José Martínez-Costas

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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  6. Monitoring Mitophagy Dynamics in Live Cells.Methods in molecular biology (Clifton, N.J.) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Mateo I Sánchez *Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15782, Santiago de, Compostela, Spain.ORCID http://orcid.org/0000-0003-1359-6969
Yolanda VidaCentro Andaluz de Nanomedicina y Biotecnología-BIONAND. Parque Tecnológico de Andalucía, c/Severo Ochoa, 35, 29590, Campanillas, Málaga, Spain.ORCID http://orcid.org/0000-0002-7004-4629
Ezequiel Pérez-InestrosaCentro Andaluz de Nanomedicina y Biotecnología-BIONAND. Parque Tecnológico de Andalucía, c/Severo Ochoa, 35, 29590, Campanillas, Málaga, Spain.
José L MascareñasCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15782, Santiago de, Compostela, Spain.
M Eugenio VázquezCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15782, Santiago de, Compostela, Spain.ORCID http://orcid.org/0000-0001-7500-985X
Ayumu Sugiura *Montreal Neurological Institute, McGill University, Montreal, QC, Canada. asugiura@med.kobe-u.ac.jp.ORCID http://orcid.org/0000-0002-4776-1478
José Martínez-CostasCentro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Bioquímica y Biología Molecular, Universidade de Santiago de Compostela, 15782, Santiago de, Compostela, Spain. jose.martinez.costas@usc.es.ORCID http://orcid.org/0000-0002-8877-7775
Universidade de Santiago de Compostela · ESAndalusian Centre for Nanomedicine and Biotechnology · ESMontreal Neurological Institute and Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MitoBlue is a fluorescent bisamidine that can be used to easily monitor the changes in mitochondrial degradation processes in different cells and cellular conditions. MitoBlue staining pattern is exceptional among mitochondrial dyes and recombinant fluorescent probes, allowing the dynamic study of mitochondrial recycling in a variety of situations in living cells. MitoBlue is a unique tool for the study of these processes that will allow the detailed characterization of communication between mitochondria and lysosomes.

Indexed as

2-NaphthylamineAmidinesAnimalsChick EmbryoFibroblastsLysosomesMicroscopy, FluorescenceMitochondria2-NaphthylamineAmidinesMitoBlue

Identifiers

PMID32103132
PMCPMC7044336
OpenAlexW3007007953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.