Trial reportScientific reports2020
Concept of a Radiofrequency Device for Osteopenia/Osteoporosis Screening.
Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 32 citations in OpenAlex.
- MRI-based pedicle bone quality score predicts cage subsidence following oblique lumbar interbody fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Pulsed radiofrequency therapy ameliorates steroid-induced osteonecrosis of the femoral head by promoting nerve growth factor production.Cytotechnology · 2026Article
- Reducing soft tissue artefacts through projection of markers and microwave imaging: An exploratory study.Scientific reports · 2025Article
- Miniaturized Dual Antiphase Patch Antenna Radiating into the Human Body at 2.4 GHz.IEEE journal of electromagnetics, RF and microwaves in medicine and biology · 2023Article
- A method based on non-ionizing microwave radiation for ancillary diagnosis of osteoporosis: a pilot study.Biomedical engineering online · 2022Article
- An amplitude-based characteristic parameter extraction algorithm for cerebral edema detection based on electromagnetic induction.Biomedical engineering online · 2021Article
- A feasibility study on microwave imaging of bone for osteoporosis monitoring.Medical & biological engineering & computing · 2021Article
- Persistent bone impairment despite long-term control of hyperprolactinemia and hypogonadism in men and women with prolactinomas.Scientific reports · 2021Article
- Visible Human Project® female surface based computational phantom (Nelly) for radio-frequency safety evaluation in MRI coils.PloS one · 2021Article
- Application of a Neural Network Classifier to Radiofrequency-Based Osteopenia/Osteoporosis Screening.IEEE journal of translational engineering in health and medicine · 2021Article
- Microwave Bone Imaging: A Preliminary Investigation on Numerical Bone Phantoms for Bone Health Monitoring.Sensors (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
Osteoporosis represents a major health problem, resulting in substantial increases in health care costs. There is an unmet need for a cost-effective technique that can measure bone properties without the use of ionizing radiation. The present study reports design, construction, and testing of a safe, and easy to use radiofrequency device to detect osteoporotic bone conditions. The device uses novel on-body antennas contacting the human wrist under an applied, operator-controlled pressure. For the dichotomous diagnostic test, we selected 60 study participants (23-94 years old, 48 female, 12 male) who could be positively differentiated between healthy and osteopenic/osteoporotic states. The band-limited integral of the transmission coefficient averaged for both wrists, multiplied by age, and divided by BMI has been used as an index. For a 100 MHz frequency band centered about 890-920 MHz, the maximum Youden's J index is 81.5%. Both the sensitivity and specificity simultaneously reach 87% given the calibration device threshold tolerance of ±3%. Our approach correlates well with the available DXA measurements and has the potential for screening patients at risk for fragility fractures, given the ease of implementation and low costs associated with both the technique and the equipment. The inclusion of radiofrequency transmission data does add supplementary useful information to the available clinical risk factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.