Evidence map›Paper›PMID 32103006›Full record

ArticleNature communications2020

c-FLIP is crucial for IL-7/IL-15-dependent NKp46

Ute Bank, Katrin Deiser, Carlos Plaza-Sirvent, Lisa Osbelt, Amelie Witte, Laura Knop, Rebecca Labrenz, Robert Jänsch, Felix Richter, Aindrila Biswas and 8 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. The cell death regulator c-FLIPJournal of molecular medicine (Berlin, Germany) · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. A Knowledge-Guided Large Language Model Framework for Microbiome-Based Disease Diagnosis.Proceedings. IEEE International Conference on Bioinformatics and Biomedicine · 2025
    Article
  8. GPX4 restricts ferroptosis of NKp46Cell death & disease · 2024
    Article
  9. Review
  10. Divergent roles for STAT4 in shaping differentiation of cytotoxic ILC1 and NK cells during gut inflammation.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  11. ILC3: a case of conflicted identity.Frontiers in immunology · 2023
    Review
  12. Review
  13. Article
  14. Dynamic Changes of NCRInflammation · 2022
    Article
  15. Innate Lymphoid Cells and Intestinal Inflammatory Disorders.International journal of molecular sciences · 2022
    Review
  16. Innate Lymphoid Cells in Crohn's Disease.Frontiers in immunology · 2020
    Review
  17. CCR8 SignalingFrontiers in immunology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 2 countries.

Ute Bank *Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Katrin Deiser *Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Carlos Plaza-SirventInstitute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Lisa OsbeltInstitute of Medical Microbiology and Hospital Hygiene, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Amelie WitteInstitute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Laura KnopInstitute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Rebecca LabrenzInstitute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.ORCID http://orcid.org/0000-0003-0119-6386
Robert JänschInstitute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Felix RichterInstitute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Aindrila BiswasInstitute of Inflammation and Neurodegeneration, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Ana C ZenclussenExperimental Obstetrics and Gynecology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Eric VivierCentre d'Immunologie de Marseille-Luminy, Aix Marseille Université, Inserm, CNRS, Marseille, France.ORCID http://orcid.org/0000-0001-7022-8287
Chiara RomagnaniInnate Immunity, German Rheumatism Research Center (DRFZ), Leibniz Association, Berlin, Germany.ORCID http://orcid.org/0000-0002-5167-7463
Anja A KühlCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt Universität zu Berlin, and Berlin Institute of Health, iPATH, Berlin, Germany.
Ildiko R DunayInstitute of Inflammation and Neurodegeneration, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.
Till StrowigMicrobial Immune Regulation Research Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.ORCID http://orcid.org/0000-0003-0185-1459
Ingo SchmitzInstitute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany.ORCID http://orcid.org/0000-0002-5360-0419
Thomas SchülerInstitute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany. thomas.schueler@med.ovgu.de.ORCID http://orcid.org/0000-0002-0567-4827
Otto-von-Guericke-Universität Magdeburg · DEHelmholtz Centre for Infection Research · DECentre National de la Recherche Scientifique · FRHumboldt-Universität zu Berlin · DELeibniz Association · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NKp46

Indexed as

AnimalsAntigens, LyApoptosisB-LymphocytesCASP8 and FADD-Like Apoptosis Regulating ProteinCells, CulturedColitisInterleukin-15Interleukin-7Killer Cells, NaturalMiceMice, KnockoutNatural Cytotoxicity Triggering Receptor 1PhosphorylationSTAT5 Transcription FactorT-LymphocytesAntigens, LyCASP8 and FADD-Like Apoptosis Regulating ProteinCflar protein, mouseInterleukin-15Interleukin-7interleukin-7, mouseNatural Cytotoxicity Triggering Receptor 1Ncr1 protein, mouseStat5a protein, mouseSTAT5 Transcription Factor

Identifiers

PMID32103006
PMCPMC7044440
OpenAlexW3008284871

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.