Evidence map›Paper›PMID 32102885›Full record

ArticleJournal of virology2020

Priming of Antiviral CD8 T Cells without Effector Function by a Persistently Replicating Hepatitis C-Like Virus.

Alex S Hartlage, Christopher M Walker, Amit Kapoor

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Pathogenesis of viral infections during pregnancy.Clinical microbiology reviews · 2024
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Animal Models Used in Hepatitis C Virus Research.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alex S HartlageCenter for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Christopher M WalkerCenter for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Amit KapoorCenter for Vaccines and Immunity, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA amit.kapoor@nationwidechildrens.org.
Nationwide Children's Hospital · USThe Ohio State University · US

Funding

Host response and liver disease in a hepatitis C-like virus rat modelR01AI137567 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI KAPOOR, AMIT · 2018 to 2022
$2.5M
Hepacivirus control by vaccine-elicited T cells.F30AI143060 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI HARTLAGE, ALEX STEPHEN · 2019 to 2022
$170k
NIAID NIH HHS F30 AI143060NIAID NIH HHS R01 AI137567
6 · The paper itself

Abstract

Immune-competent animal models for the hepatitis C virus (HCV) are nonexistent, impeding studies of host-virus interactions and vaccine development. Experimental infection of laboratory rats with a rodent hepacivirus isolated from

Indexed as

Adaptive ImmunityAnimalsAntiviral AgentsCD8-Positive T-LymphocytesCytokinesDisease Models, AnimalFemaleHepacivirusHepatitis CHistocompatibility Antigens Class IHost-Pathogen InteractionsLiverRatsVaccinationViremiaVirus ReplicationAntiviral AgentsCytokinesHistocompatibility Antigens Class Ianimal modelsantiviral agentsantiviralshepacivirushepatitis C virusT cellsvaccines

Identifiers

PMID32102885
PMCPMC7199419
OpenAlexW3007022558

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.