Evidence map›Paper›PMID 32102875›Full record

ArticleJournal of virology2020

Chikungunya Virus Evades Antiviral CD8

Bennett J Davenport, Christopher Bullock, Mary K McCarthy, David W Hawman, Kenneth M Murphy, Ross M Kedl, Michael S Diamond, Thomas E Morrison

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Review
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  7. Article
  8. Article
  9. Article
  10. Chikungunya virus-specific CD4Cell reports. Medicine · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Ly6CCell reports · 2024
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Bennett J DavenportDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Christopher BullockDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Mary K McCarthyDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
David W HawmanDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Kenneth M MurphyDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Ross M KedlDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Michael S DiamondDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Thomas E MorrisonDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA thomas.morrison@cuanschutz.edu.
University of Colorado Denver · USWashington University in St. Louis · USHoward Hughes Medical Institute · US

Funding

Research Training in Rheumatology INCLUDE Down Syndrome SupplementT32AR007534 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI Kristine A. Kuhn · 1986 to 2026
$6.1M
Impairment of B cell Responses by Pathogenic Chikungunya VirusesR01AI141436 · NIAID · UNIVERSITY OF COLORADO DENVER · PI DIAMOND, MICHAEL S, MORRISON, THOMAS E · 2019 to 2023
$3.2M
Molecular Basis of cDC1 DevelopmentR01AI162643 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2022 to 2025
$2.8M
Function of Wdfy4 in cross-presentation and immunityR01AI150297 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2019 to 2023
$2.5M
Understanding the Mechanisms of DC Licensing in CD8 T Cell PrimingR01CA248919 · NCI · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2021 to 2025
$2.3M
Mechanisms of immune suppression during arthritogenic alphavirus infectionsR01AI108725 · NIAID · UNIVERSITY OF COLORADO DENVER · PI MORRISON, THOMAS E · 2014 to 2018
$1.9M
NCI NIH HHS R01 CA248919NIAID NIH HHS R01 AI108725NIAID NIH HHS R01 AI141436NIAID NIH HHS R01 AI150297NIAID NIH HHS R01 AI162643NIAMS NIH HHS T32 AR007534
6 · The paper itself

Abstract

Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes explosive epidemics of a febrile illness characterized by debilitating arthralgia and arthritis that can endure for months to years following infection. In mouse models, CHIKV persists in joint tissues for weeks to months and is associated with chronic synovitis. Using a recombinant CHIKV strain encoding a CD8

Indexed as

Adaptive ImmunityAdoptive TransferAnimalsAntibodies, ViralAntiviral AgentsArthritisCD8-Positive T-LymphocytesChikungunya FeverChikungunya virusDisease Models, AnimalEpitopes, T-LymphocyteFemaleImmunizationJointsLectins, C-TypeMaleAntibodies, ViralAntiviral AgentsCLEC12A protein, humanEpitopes, T-LymphocyteLectins, C-TypeReceptors, MitogenalphavirusCD8 T cellchikungunya virusviral persistence

Identifiers

PMID32102875
PMCPMC7163133
OpenAlexW3006687635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.