Evidence map›Paper›PMID 32102783›Full record

ArticleDisease models & mechanisms2020

DnaJ-PKAc fusion induces liver inflammation in a zebrafish model of fibrolamellar carcinoma.

Sofia de Oliveira, Ruth A Houseright, Benjamin G Korte, Anna Huttenlocher

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease models & mechanisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. A framework for fibrolamellar carcinoma research and clinical trials.Nature reviews. Gastroenterology & hepatology · 2022
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sofia de OliveiraDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI 53706, USA sofia.deoliveira@einsteinmed.org huttenlocher@wisc.edu.ORCID 0000-0003-0893-111X
Ruth A HouserightDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-8209-372X
Benjamin G KorteDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Anna HuttenlocherDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI 53706, USA sofia.deoliveira@einsteinmed.org huttenlocher@wisc.edu.ORCID 0000-0001-7940-6254
University of Wisconsin–Madison · US

Funding

Training in Cancer Biology Training GrantT32CA009135 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI SUGDEN, WILLIAM M. · 1985 to 2024
$10.4M
RESEARCH TRAINING IN HEMATOLOGYT32HL007899 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Jane Ellen Churpek · 1998 to 2026
$8.2M
ADHESIVE REGULATION DURING CELL MIGRATIONR01CA085862 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Anna Huttenlocher · 2000 to 2026
$7.3M
NCI NIH HHS R01 CA085862NCI NIH HHS T32 CA009135NHLBI NIH HHS T32 HL007899
6 · The paper itself

Abstract

Fibrolamellar carcinoma (FLC) is a rare liver cancer that affects adolescents and young adults. Genomic analysis of FLC has revealed a 400 kb deletion in chromosome 19 that leads to the chimeric transcript

Indexed as

Immunity, InnateAgingAmino Acid SequenceAnimalsCarcinoma, HepatocellularCaspasesDisease Models, AnimalDisease ProgressionHepatocytesInflammationLiverMacrophagesOncogene Proteins, FusionTumor Necrosis Factor-alphaZebrafishCaspasesOncogene Proteins, FusionTumor Necrosis Factor-alphaEarly progressionFibrolamellar carcinomaInflammationLiverNon-invasive imaging

Identifiers

PMID32102783
PMCPMC7197716
OpenAlexW3007525183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.