Trial reportPsychological medicine2021
Cognitive function after electroconvulsive therapy for depression: relationship to clinical response.
Trial report in Psychological medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed.
- Longitudinal Neurocognitive Effects of Combined Electroconvulsive Therapy (ECT) and Pharmacotherapy in Major Depressive Disorder in Older Adults: Phase 2 of the PRIDE Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022Trial
- Does the Loss of Autobiographical Memories Contribute to the Therapeutic Effect of Electroconvulsive Therapy?Acta psychiatrica Scandinavica · 2026Article
- Electroconvulsive therapy and the WHO: patients and professionals deserve expertise and facts, not ideology.Der Nervenarzt · 2026Article
- Electroconvulsive therapy and autobiographical memory.Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2026Article
- Improvement in Depressive Symptoms Is Not Associated with the Severity of Autobiographical Amnesia Following Electroconvulsive Therapy-A Preliminary Report from Naturalistic Prospective Observational Study.Journal of clinical medicine · 2025Article
- Effects of modifying the pulse width on cognitive side effects with electroconvulsive therapy for schizophrenia.Schizophrenia research. Cognition · 2025Article
- Outpatient Management of Bipolar Disorder in Older Adults.Current psychiatry reports · 2025Review
- Clinical implications of admission anemia for electroconvulsive therapy planning in adolescent major depressive disorder: identifying vulnerable subgroups with poorer response.Frontiers in psychiatry · 2025Article
- Clinical practice guidelines on the assessment and management of cognitive impairment in major depressive disorder.Indian journal of psychiatry · 2025Article
- Anesthetic Influence on Electroconvulsive Therapy: A Comprehensive Review.Neuropsychiatric disease and treatment · 2024Review
- Fronto-medial electrode placement for electroconvulsive treatment of depression.Frontiers in neuroscience · 2022Article
- Longitudinal Improvement of Neurocognition after Electroconvulsive Therapy in Bipolar Depression.Case reports in psychiatry · 2021Article
- Assessment of the Risk of Depression in Residents Staying at Long-Term Care Institutions in Poland During the COVID-19 Pandemic Depending on the Quality of Cognitive Functioning.Frontiers in psychology · 2021Article
- Effects of electrode placement on symptoms, memory, and sustainment of results after electroconvulsive therapy- A comparative study.Industrial psychiatry journalArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundAs uncertainty remains about whether clinical response influences cognitive function after electroconvulsive therapy (ECT) for depression, we examined the effect of remission status on cognitive function in depressed patients 4 months after a course of ECT.
methodA secondary analysis was undertaken on participants completing a randomised controlled trial of ketamine augmentation of ECT for depression who were categorised by remission status (MADRS ⩽10 v. >10) 4 months after ECT. Cognition was assessed with self-rated memory and neuropsychological tests of anterograde verbal and visual memory, autobiographical memory, verbal fluency and working memory. Patients were assessed through the study, healthy controls on a single occasion, and compared using analysis of variance.
resultsAt 4-month follow-up, remitted patients (N = 18) had a mean MADRS depression score of 3.8 (95% CI 2.2-5.4) compared with 27.2 (23.0-31.5) in non-remitted patients (N = 19), with no significant baseline differences between the two groups. Patients were impaired on all cognitive measures at baseline. There was no deterioration, with some measures improving, 4-months after ECT, at which time remitted patients had significantly improved self-rated memory, anterograde verbal memory and category verbal fluency compared with those remaining depressed. Self-rated memory correlated with category fluency and autobiographical memory at follow-up.
conclusionsWe found no evidence of persistent impairment of cognition after ECT. Achieving remission improved subjective memory and verbal memory recall, but other aspects of cognitive function were not influenced by remission status. Self-rated memory may be useful to monitor the effects of ECT on longer-term memory.
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