Evidence map›Paper›PMID 32102721›Full record

ArticleEpidemiology and infection2020

Maternal caesarean section infection (MACSI) in Sierra Leone: a case-control study.

F Di Gennaro, C Marotta, L Pisani, N Veronese, V Pisani, V Lippolis, G Pellizer, D Pizzol, F Tognon, D F Bavaro and 7 more

Open access · goldAbstract read
In one paragraph

Article in Epidemiology and infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Laparoscopy in Low-Income Countries: 10-Year Experience and Systematic Literature Review.International journal of environmental research and public health · 2021
    Pooled it
  4. Trial
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  9. Review
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  11. Antimicrobial Resistance in Sub-Saharan Africa: A Comprehensive Landscape Review.The American journal of tropical medicine and hygiene · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 4 countries.

F Di GennaroClinic of Infectious Diseases, University of Bari, Bari, Italy.ORCID 0000-0003-3453-5647
C MarottaOperational Research Unit, Doctors with Africa CUAMM, Padua, Italy.
L PisaniOperational Research Unit, Doctors with Africa CUAMM, Padua, Italy.
N VeronesePrimary Care Department, Unità Locale Socio Sanitaria 3 'Serenissima', Venice, Italy.
V PisaniOperational Research Unit, Doctors with Africa CUAMM, Freetown, Sierra Leone.
V LippolisMater dei Hospital, Bari, Italy.
G PellizerOperational Research Unit, Doctors with Africa CUAMM, Padua, Italy.
D PizzolOperational Research Unit, Doctors with Africa CUAMM, Padua, Italy.
F TognonOperational Research Unit, Doctors with Africa CUAMM, Padua, Italy.
D F BavaroClinic of Infectious Diseases, University of Bari, Bari, Italy.ORCID 0000-0002-4833-7118
F OlivaOperational Research Unit, Doctors with Africa CUAMM, Freetown, Sierra Leone.
S PonteOperational Research Unit, Doctors with Africa CUAMM, Freetown, Sierra Leone.
P Nanka BruceUNFPA, United Nations Population Fund, Freetown, Sierra Leone.
L MonnoClinic of Infectious Diseases, University of Bari, Bari, Italy.
A SaracinoClinic of Infectious Diseases, University of Bari, Bari, Italy.
M M KoromaPrincess Christian Maternity Hospital (PCMH), Freetown, Sierra Leone.
G PutotoOperational Research Unit, Doctors with Africa CUAMM, Padua, Italy.
Doctors with Africa Cuamm · ITSierra Leone Urban Research Centre · SLUniversity of Bari Aldo Moro · ITSt John of God Hospital Sierra Leone · SLUnited Nations Population Fund · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sierra Leone is the country with highest maternal mortality and infections are the underlying cause in 11% of maternal deaths, but the real burden remains unknown. This study aims to determine the incidence and risk factors of surgical site infection (SSI) post-caesarean section (CS) in women admitted to Princess Christian Maternity Hospital (PCMH) in Freetown, Sierra Leone. A prospective case-control (1:3 ratio) study was implemented from 1 May 2018 to 30 April 2019 and 11 women presenting with suspected or confirmed infection post-CS were screened for inclusion as a case. For each case, three patients undergoing CS on the same day and admitted to the same ward, but not presenting with SSI, were selected as controls. The post-CS infection rate was 10.9%. Two hundred and fifty-four clinically confirmed cases were enrolled and matched with 762 control patients. By multivariable analysis, the risk factors for SSI were: being single (odds ratio (OR) 1.48, 95% confidence interval (CI) 1.36-1.66), low education level (OR 1.68, 95% CI 1.55-1.84), previous CS (OR 1.27, 95% CI 1.10-1.52), presenting with premature membranes rupture (OR 1.49, 95% CI 1.18-1.88), a long decision-incision time (OR 2.08, 95% CI 1.74-2.24) and a high missing post-CS antibiotic doses rate (OR 2.52, 95% CI 2.10-2.85).

Indexed as

AdultCase-Control StudiesCesarean SectionFemaleHospitalsHumansIncidencePregnancyProspective StudiesRisk FactorsSierra LeoneSurgical Wound InfectionSurvival AnalysisAntibioticmaternal deathSierra Leonesurgical site infection

Identifiers

PMID32102721
PMCPMC7058652
OpenAlexW3008511552

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.