Evidence map›Paper›PMID 32102643›Full record

Observational studyCritical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine2020

Autonomic function, postprandial hypotension and falls in older adults at one year after critical illness.

Yasmine Ali Abdelhamid, Luke M Weinel, Seva Hatzinikolas, Matthew Summers, Thu Anh Ngoc Nguyen, Palash Kar, Liza K Phillips, Michael Horowitz, Adam M Deane, Karen L Jones

Open access · greenAbstract readObservational Study
PubMed Full text at PMC
In one paragraph

Observational study in Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yasmine Ali AbdelhamidDiscipline of Acute Care Medicine, University of Adelaide, Adelaide, SA, Australia. yasmine.aliabdelhamid@mh.org.au.
Luke M WeinelDiscipline of Acute Care Medicine, University of Adelaide, Adelaide, SA, Australia.
Seva HatzinikolasCentre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, SA, Australia.
Matthew SummersDiscipline of Acute Care Medicine, University of Adelaide, Adelaide, SA, Australia.
Thu Anh Ngoc NguyenDiscipline of Acute Care Medicine, University of Adelaide, Adelaide, SA, Australia.
Palash KarDiscipline of Acute Care Medicine, University of Adelaide, Adelaide, SA, Australia.
Liza K PhillipsCentre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, SA, Australia.
Michael HorowitzCentre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, SA, Australia.
Adam M DeaneDiscipline of Acute Care Medicine, University of Adelaide, Adelaide, SA, Australia.
Karen L JonesCentre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, SA, Australia.
University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePostprandial hypotension occurs frequently in older survivors of critical illness at 3 months after discharge. We aimed to determine whether postprandial hypotension and its predictors - gastric dysmotility and cardiovascular autonomic dysfunction - persist or resolve as older survivors of critical illness recover, and whether postprandial hypotension after intensive care unit (ICU) discharge is associated with adverse outcomes at 12 months.

designProspective observational study.

settingTertiary medical-surgical ICU.

participantsOlder adults (aged ≥ 65 years) who had been studied 3 months after ICU discharge and who returned for a follow-up study at 12 months after discharge.

main outcome measuresOn both occasions after fasting overnight, participants consumed a 300 mL drink containing 75 g glucose, radiolabelled with 20 MBq

resultsOut of 35 older adults studied at 3 months, 22 returned for the follow-up study at 12 months. Postprandial hypotension was evident in 29% of participants (95% CI, 14-44%) at 3 months and 10% of participants (95% CI, 1-30%) at 12 months. Postprandial hypotension at 3 months was associated with a more than threefold increase in the risk of falls in the year after ICU discharge (relative risk, 3.7 [95% CI, 1.6-8.8];

conclusionsIn older adults who were evaluated 3 and 12 months after ICU discharge, postprandial hypotension at 3 months was associated with an increased risk of subsequent falls, but the prevalence of postprandial hypotension decreased with time.

Indexed as

Critical IllnessPostprandial PeriodAccidental FallsAgedAutonomic Nervous SystemAutonomic Nervous System DiseasesBlood PressureFemaleFollow-Up StudiesHumansHypotensionMaleProspective StudiesQuality of Life

Identifiers

PMID32102643
PMCPMC10692471
OpenAlexW3012489732

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.