Observational studyCritical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine2020
Prospective observational study of mechanical cardiopulmonary resuscitation, extracorporeal membrane oxygenation and early reperfusion for refractory cardiac arrest in Sydney: the 2CHEER study.
Observational study in Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- The impact of selection criteria and study design on reported survival outcomes in extracorporeal oxygenation cardiopulmonary resuscitation (ECPR): a systematic review and meta-analysis.Scandinavian journal of trauma, resuscitation and emergency medicine · 2021Pooled it
- Determining Access for a City-Wide Extracorporeal Cardiopulmonary Resuscitation (ECPR) Initiative Using Geospatial Analysis.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026Article
- Prehospital initiation of extracorporeal life support for refractory out-of-hospital cardiac arrest-results of a prospective observational study.Critical care (London, England) · 2026Observational
- Cost effectiveness of pre-hospital extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest - An analysis of the PRECARE study.Resuscitation plus · 2026Article
- Estimated caseload for a rotary wing prehospital extra-corporeal cardio-pulmonary resuscitation service in North West England: A retrospective eligibility study.Resuscitation plus · 2025Article
- Conventional Cardiopulmonary Resuscitation Versus Extracorporeal Membrane Oxygenation-Assisted CPR in Children: A Retrospective Analysis of Outcomes and Factors Associated with Conversion from the Former to the Latter.Children (Basel, Switzerland) · 2025Article
- Extracorporeal Cardiopulmonary Resuscitation for 78-min Cardiac Arrest due to Suspected Cerebral Venous Sinus Thrombosis.Case reports in critical care · 2025Article
- Implementing enhanced extracorporeal membrane oxygenation for CPR (ECPR) in the emergency department.International journal of emergency medicine · 2024Article
- A case report of point-of-care ultrasound directed thrombectomy: a reversible cause of cardiac arrest managed with extracorporeal membrane oxygenation cannulation.Clinical and experimental emergency medicine · 2024Article
- Extracorporeal cardiopulmonary resuscitation dissemination and integration with organ preservation in the USA: ethical and logistical considerations.Critical care (London, England) · 2023Review
- Improving access to extracorporeal membrane oxygenation for out of hospital cardiac arrest: pre-hospital ECPR and alternate delivery strategies.Scandinavian journal of trauma, resuscitation and emergency medicine · 2022Article
- Cost-effectiveness of extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest: A modelling study.Resuscitation plus · 2022Article
- Out-of-hospital cardiac arrest outcomes, end-tidal carbon dioxide and extracorporeal cardiopulmonary resuscitation eligibility: New South Wales pilot data.Emergency medicine Australasia : EMA · 2022Article
- The effect of a structured ECPR protocol aided by specific simulation training in a quaternary ECMO centre: A retrospective pre-post study.Resuscitation plus · 2022Article
- A novel strategy sequentially linking mechanical cardiopulmonary resuscitation with extracorporeal cardiopulmonary resuscitation optimizes prognosis of refractory cardiac arrest: an illustrative case series.European journal of medical research · 2022Article
- Out of hospital cardiac arrest in Western Sydney-an analysis of outcomes and estimation of future eCPR eligibility.BMC emergency medicine · 2022Observational
- Extracorporeal life support in adult patients with out-of-hospital cardiac arrest.Singapore medical journal · 2021Article
- Feasibility of extracorporeal membrane oxygenation cardiopulmonary resuscitation by low volume centers in Belgium.Journal of the American College of Emergency Physicians open · 2021Article
- Mechanical circulatory support for refractory out-of-hospital cardiac arrest: a Danish nationwide multicenter study.Critical care (London, England) · 2021Observational
- Extracorporeal cardiopulmonary resuscitation for adults with shock-refractory cardiac arrest.Journal of the American College of Emergency Physicians open · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with prolonged cardiac arrest that is not responsive to conventional cardiopulmonary resuscitation have poor outcomes. The use of extracorporeal membrane oxygenation (ECMO) in refractory cardiac arrest has shown promising results in carefully selected cases. We sought to validate the results from an earlier extracorporeal cardiopulmonary resuscitation (ECPR) study (the CHEER trial).
methodsProspective, consecutive patients with refractory in-hospital (IHCA) or out-of-hospital cardiac arrest (OHCA) who met predefined inclusion criteria received protocolised care, including mechanical cardiopulmonary resuscitation, initiation of ECMO, and early coronary angiography (if an acute coronary syndrome was suspected).
resultsTwenty-five patients were enrolled in the study (11 OHCA, 14 IHCA); the median age was 57 years (interquartile range [IQR], 39-65 years), and 17 patients (68%) were male. ECMO was established in all patients, with a median time from arrest to ECMO support of 57 minutes (IQR, 38-73 min). Percutaneous coronary intervention was performed on 18 patients (72%). The median duration of ECMO support was 52 hours (IQR, 24-108 h). Survival to hospital discharge with favourable neurological recovery occurred in 11/25 patients (44%, of which 72% had IHCA and 27% had OHCA). When adjusting for lactate, arrest to ECMO flow time was predictive of survival (odds ratio, 0.904;
conclusionECMO for refractory cardiac arrest shows promising survival rates if protocolised care is applied in conjunction with predefined selection criteria.
Indexed as
Identifiers
32102640PMC10692455W3010695845What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.