Evidence map›Paper›PMID 32102500›Full record

ReviewAsian Pacific journal of cancer prevention : APJCP2020

LncRNAs as Potential Therapeutic Targets in Thyroid Cancer.

Zeeshan Javed, Faiez Ahmed Shah, Sadegh Rajabi, Qamar Raza, Zaheer Iqbal, Mukhtar Ullah, Touqeer Ahmad, Bahare Salehi, Mehdi Sharifi-Rad, Raffaele Pezzani and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Asian Pacific journal of cancer prevention : APJCP, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  11. LncRNA HOTAIR enhances RCC2 to accelerate cervical cancer progression by sponging miR-331-3p.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
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  13. Review
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  16. Expression ofMolecular medicine reports · 2022
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 4 countries.

Zeeshan JavedOffice for Research Innovation and Commercialization Lahore Garrison University, Lahore, Pakistan.
Faiez Ahmed ShahDepartment of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.
Sadegh RajabiDepartment of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Qamar RazaInstitute of Biochemistry and Biotechnology,University of Veterinary and Animal Sciences, Lahore, Pakistan.
Zaheer IqbalCenter for Excellence in Molecular Biology, University of the Punjab Lahore, Lahore, Pakistan.
Mukhtar UllahOffice for Research Innovation and Commercialization Lahore Garrison University, Lahore, Pakistan.
Touqeer AhmadDepartment of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.
Bahare SalehiStudent Research Committee, School of Medicine, Bam University of Medical Sciences, Bam, Iran.
Mehdi Sharifi-RadDepartment of Medical Parasitology, Kerman University of Medical Sciences, Kerman, Iran.
Raffaele PezzaniOU Endocrinology, Dept. Medicine (DIMED), University of Padova, via Ospedale 105, 35128 Padova, Italy.
Farooq YaqoobCenter for Excellence in Molecular Biology, University of the Punjab Lahore, Lahore, Pakistan.
Haleema SadiaOffice for Research Innovation and Commercialization Lahore Garrison University, Lahore, Pakistan.
Marcello IritiDepartment of Agricultural and Environmental Sciences, Milan State University, 20133 Milan, Italy.
Javad Sharifi-RadPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
William C ChoDepartment of Clinical Oncology, Queen Elizabeth Hospital, 30 Gascoigne Road, Hong Kong, China.
Quaid-i-Azam University · PKShahid Beheshti University of Medical Sciences · IRBam University of Medical Sciences · IRKerman University of Medical Sciences · IRQueen Elizabeth Hospital · CNUniversity of Milan · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid cancer (TC) is the most common cancer of endocrine system. TC can be subdivided into 4 different entities, papillary, follicular, medullary and anaplastic thyroid cancer. Among them, anaplastic thyroid cancer has the poorest prognosis. Exploring new therapeutic approach may entail favorable prediction as well as increasing overall survival rate of patients. Long non-coding RNAs (lncRNAs), have vast implications in different cancer types. Although they are not transcribed into proteins, they can act as a harness in regulating a plethora of biological functions. They have been implicated in a decisive role in gene expression via modulation of both coding and non-coding RNAs. This article discuss the multi-facet role of lncRNA in thyroid cancer biology.<br />.

Indexed as

Molecular Targeted TherapyAntineoplastic AgentsBiomarkers, TumorHumansPrognosisRNA, Long NoncodingThyroid NeoplasmsAntineoplastic AgentsBiomarkers, TumorRNA, Long NoncodingDiagnosisgenetic alterationslncRNAThyroid cancertreatment

Identifiers

PMID32102500
PMCPMC7332117
OpenAlexW3007426880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.