Evidence map›Paper›PMID 32102499›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2020

Systematic Analysis of the Application and Inappropriate Use/Misuse of Statistics in Cholangiocarcinoma Research in Southeast Asia.

Panida Kongjam, Lakshmanan Jeyaseelan, Wanna Chaijaroenkul, Kesara Na-Bangchang

Open access · goldAbstract read
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Panida KongjamChulabhorn International College of Medicine, Thammasat University, Paholyothin Road, Klongluang, Pathumthani Thailand.
Lakshmanan JeyaseelanDepartment of Biostatistics, Christian Medical College, Vellore-632 002, India.
Wanna ChaijaroenkulChulabhorn International College of Medicine, Thammasat University, Paholyothin Road, Klongluang, Pathumthani Thailand.
Kesara Na-BangchangChulabhorn International College of Medicine, Thammasat University, Paholyothin Road, Klongluang, Pathumthani Thailand.ORCID 0000-0001-6389-0897
Thammasat University · THChristian Medical College, Vellore · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the study was to perform a systematic review of research articles related to cholangiocarcinoma (CCA), the bile duct cancer in Southeast Asian (SEA) countries published during 2010-2015 including analysis of inappropriate use/misuse of statistics.

methodsResearch articles were retrieved from the PubMed database using different 'keywords' for seven research disciplines/categories in biomedical sciences (medicine/physiology, epidemiology, immunology, pharmacology and toxicology, diagnosis/diagnostics, drug resistance, and biochemistry).

resultsA total of 353 articles were finally included in the analysis based on the pre-defined eligibility criteria. Most were articles of which the studies were conducted in Thailand (335 articles, 94.90%). Disease diagnosis/diagnostics (n=266, 75.35%), biochemistry (n =223, 63.17%), and pharmacology and toxicology (n =218, 61.76%) were the three main research disciplines/categories for CAA conducted in SEA countries during 2010-2015. Thailand was the country which most published CCA-related research articles in all disciplines/categories. Drug resistance was the research category that most applied both descriptive and inferential statistics (100%). The student's t-test was the most applied test (35.13%). Inappropriate use/misuse of statistics in all types was highest in diagnosis/diagnostics (73.59%) and pharmacology and toxicology (73.06%) research disciplines/categories and was lowest in medicine/pathophysiology (0.26%). Inappropriate use/misuse in almost all types (seven types) was found in the diagnosis/diagnostics category.

conclusionResults of the systematic analysis of CCA-related research articles published from the ten SEA countries during 2010-2015 reveal high rates of inappropriate use/misuse of statistics. The readers should be aware of the reliability of the articles and the possibility of wrong interpretation and conclusion of these articles.

Indexed as

Drug Resistance, NeoplasmBile Duct NeoplasmsCholangiocarcinomaComputational BiologyData Interpretation, StatisticalHumansPrognosisReproducibility of ResultsResearch ReportStatistics as TopicSurvival RateThailandcholangiocarcinomaStatistical misusestatisticsSystematic review

Identifiers

PMID32102499
PMCPMC7332113
OpenAlexW3006952525

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.