Evidence map›Paper›PMID 32102427›Full record

ArticleNutrients2020

The Association of Vitamin D Status with Lipid Profile and Inflammation Biomarkers in Healthy Adolescents.

Amirhossein Yarparvar, Ibrahim Elmadfa, Abolghassem Djazayery, Zahra Abdollahi, Forouzan Salehi

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Amirhossein YarparvarSchool of Nutrition, University of Vienna, 1090 Vienna, Austria.
Ibrahim ElmadfaSchool of Nutrition, University of Vienna, 1090 Vienna, Austria.
Abolghassem DjazayerySchool of Nutrition and Dietetics, Tehran University of Medical Science, Tehran 14155/6117, Iran.
Zahra AbdollahiNutrition Department of the Ministry of health and Medical Education, Tehran 1467664961, Iran.
Forouzan SalehiDeputy Director of Family Health Department of the Ministry of health and Medical Education, Tehran 1467664961, Iran.
Ministry of Health and Medical Education · IRUniversity of Vienna · ATUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association between vitamin D status and inflammatory biomarkers and lipid profile is not well known, especially in adolescents. Therefore, the aim of the current study is to investigate the association of vitamin D status with serum lipids and inflammatory biomarkers, including IL-10, IL-6, hsCRP, and TNFR-2, in male adolescents. METHODS AND MATERIALS: A sample of seventy-one high school male students, aged 17 years old, from a high school in Tehran were enrolled in the study. They were divided into four groups including group with serum vitamin D below 25 (ng/mL) (SVD < 25;

resultsIn the (SVD < 25) group, the serum level of TNFR-2 was significantly higher compared to that in the (SVD ≥ 25) group. There was a significant negative association between serum TNFR-2 and vitamin D levels in the whole sample. We found significant lower levels of IL-10 in positive-hsCRP group compared to the negative-hsCRP group. In addition, there was a significant negative correlation between the serum vitamin D level and hsCRP in both hsCRP groups. The HDL level was lower in the (SVD < 25) group compared to that in the (SVD ≥ 25) group. Finally, there was a negative correlation between the serum HDL and hsCRP levels in the positive-hsCRP subjects.

conclusionBased on the findings it can be concluded that serum vitamin D affects HDL and inflammation status. Although serum levels of HDL and inflammation status are both predictors of metabolic syndrome and cardiovascular disease, further studies are needed to prove it, especially in adolescents.

Indexed as

AdolescentBiomarkersC-Reactive ProteinDietHumansInflammationLipidsLipoproteins, HDLLipoproteins, VLDLMaleVitamin DBiomarkersC-Reactive ProteinLipidsLipoproteins, HDLLipoproteins, VLDLVitamin DAdolescentInflammationlipid profileVitamin D status

Identifiers

PMID32102427
PMCPMC7071498
OpenAlexW3006862216

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.