Evidence map›Paper›PMID 32102230›Full record

ArticleViruses2020

Substantial Antigenic Drift in the Hemagglutinin Protein of Swine Influenza A Viruses.

Pia Ryt-Hansen, Anders Gorm Pedersen, Inge Larsen, Charlotte Sonne Kristensen, Jesper Schak Krog, Silke Wacheck, Lars Erik Larsen

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

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  15. Review of genome sequencing technologies in molecular characterization of influenza A viruses in swine.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Pia Ryt-HansenNational Veterinary Institute, Technical University of Denmark, Kemitorvet Building 204, DK-2800 Kongens Lyngby, Denmark.
Anders Gorm PedersenDepartment of Health Technology, Section for Bioinformatics, Technical University of Denmark, Kemitorvet Building 208, DK-2800 Kongens Lyngby, Denmark.
Inge LarsenDepartment of Veterinary and Animal Sciences, University of Copenhagen, Grønnegårdsvej 2, DK-1870 Frederiksberg C, Denmark.
Charlotte Sonne KristensenSEGES, Danish Pig Research Centre, Agro Food Park 15, DK-8200 Aarhus, Denmark.
Jesper Schak KrogStatens Serum Institut, Artillerivej 5, DK-2300 Copenhagen S.
Silke WacheckCeva Santé Animale 10 Avenue de la Ballastière, 33500 Libourne, France.
Lars Erik LarsenDepartment of Veterinary and Animal Sciences, University of Copenhagen, Grønnegårdsvej 2, DK-1870 Frederiksberg C, Denmark.ORCID 0000-0003-0730-5555
University of Copenhagen · DKDépartement Santé Animale · FRKnowledge Centre for Agriculture · DKStatens Serum Institut · DKTechnical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The degree of antigenic drift in swine influenza A viruses (swIAV) has historically been regarded as minimal compared to that of human influenza A virus strains. However, as surveillance activities on swIAV have increased, more isolates have been characterized, revealing a high level of genetic and antigenic differences even within the same swIAV lineage. The objective of this study was to investigate the level of genetic drift in one enzootically infected swine herd over one year. Nasal swabs were collected monthly from sows (

Indexed as

Genetic DriftMutationPhylogenyAmino Acid SubstitutionAnimalsAnimals, NewbornAntigens, ViralEvolution, MolecularFemaleHemagglutinin Glycoproteins, Influenza VirusNoseOrthomyxoviridae InfectionsSwineAntigens, ViralHemagglutinin Glycoproteins, Influenza Virusantigenic driftenzootic infectionsgenetic drifthemagglutininimmune escape variantsmolecular clockselectionsowssubstitution rateswine influenza A virus

Identifiers

PMID32102230
PMCPMC7077184
OpenAlexW3007666545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.