Evidence map›Paper›PMID 32102213›Full record

ArticleInternational journal of molecular sciences2020

Augmenting Vacuolar H

Shujin Wang, Li-Yen Wong, Dietbert Neumann, Yilin Liu, Aomin Sun, Gudrun Antoons, Agnieszka Strzelecka, Jan F C Glatz, Miranda Nabben, Joost J F P Luiken

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Role of STIM1 in the Regulation of Cardiac Energy Substrate Preference.International journal of molecular sciences · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Insulin signaling in the heart.American journal of physiology. Endocrinology and metabolism · 2021
    Review
  14. Article
  15. Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Shujin WangDepartment of Genetics & Cell Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6200-MD Maastricht, The Netherlands.
Li-Yen WongDepartment of Genetics & Cell Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6200-MD Maastricht, The Netherlands.
Dietbert NeumannDepartments of Pathology, CARIM School for Cardiovascular Diseases, Maastricht University, 6200-MD Maastricht, The Netherlands.ORCID 0000-0002-4316-684X
Yilin LiuDepartment of Genetics & Cell Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6200-MD Maastricht, The Netherlands.
Aomin SunDepartment of Genetics & Cell Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6200-MD Maastricht, The Netherlands.
Gudrun AntoonsDepartments of Physiology, CARIM School for Cardiovascular Diseases, Maastricht University, 6200-MD Maastricht, The Netherlands.
Agnieszka StrzeleckaDepartment of Genetics & Cell Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6200-MD Maastricht, The Netherlands.
Jan F C GlatzDepartment of Genetics & Cell Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6200-MD Maastricht, The Netherlands.
Miranda NabbenDepartment of Genetics & Cell Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6200-MD Maastricht, The Netherlands.ORCID 0000-0002-5691-1634
Joost J F P LuikenDepartment of Genetics & Cell Biology, Faculty of Health, Medicine and Life Sciences, Maastricht University, 6200-MD Maastricht, The Netherlands.
Maastricht University · NLUniversity Medical Center · US

Funding

a Dekker grant from the Dutch Heart Foundation nr. 2019T041
6 · The paper itself

Abstract

The diabetic heart is characterized by a shift in substrate utilization from glucose to lipids, which may ultimately lead to contractile dysfunction. This substrate shift is facilitated by increased translocation of lipid transporter CD36 (SR-B2) from endosomes to the sarcolemma resulting in increased lipid uptake. We previously showed that endosomal retention of CD36 is dependent on the proper functioning of vacuolar H

Indexed as

Lipid MetabolismAnimalsBiological TransportCD36 AntigensEndosomesGlucoseGlucose Transporter Type 4HumansInduced Pluripotent Stem CellsInsulin ResistanceLipid Accumulation ProductLipidsMaleMyocardial ContractionMyocytes, CardiacPhosphotransferasesCD36 AntigensGlucoseGlucose Transporter Type 4LipidsPhosphotransferasesSLC2A4 protein, humanTriglyceridesVacuolar Proton-Translocating ATPasescontractile functiondiabetic heartinsulin resistancelipid accumulationvacuolar H+-ATPase

Identifiers

PMID32102213
PMCPMC7073192
OpenAlexW3007494275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.