Evidence map›Paper›PMID 32101684›Full record

ArticleBiochemistry2020

IpdE1-IpdE2 Is a Heterotetrameric Acyl Coenzyme A Dehydrogenase That Is Widely Distributed in Steroid-Degrading Bacteria.

John E Gadbery, James W Round, Tianao Yuan, Matthew F Wipperman, Keith T Story, Adam M Crowe, Israel Casabon, Jie Liu, Xinxin Yang, Lindsay D Eltis and 1 more

Abstract read
In one paragraph

Article in Biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Journal of bacteriology · 2025
    Review
  3. Article
  4. Article
  5. Insight into Different Stages of Steroid Degradation in ThermophilicInternational journal of molecular sciences · 2022
    Article
  6. Article
  7. Comparative Analysis of Bile-Salt Degradation inApplied and environmental microbiology · 2021
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

John E GadberyDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794-3400, United States.ORCID 0000-0002-8998-2658
James W RoundDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Tianao YuanDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794-3400, United States.ORCID 0000-0002-4700-8654
Matthew F WippermanDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794-3400, United States.ORCID 0000-0003-1436-3366
Keith T StoryDepartment of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Adam M CroweDepartment of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.ORCID 0000-0002-5487-2520
Israel CasabonDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Jie LiuDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Xinxin YangDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794-3400, United States.ORCID 0000-0002-5162-5030
Lindsay D EltisDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.ORCID 0000-0002-6774-8158
Nicole S SampsonDepartment of Chemistry, Stony Brook University, Stony Brook, New York 11794-3400, United States.ORCID 0000-0002-2835-7760
University of British Columbia · CAStony Brook University · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Life Science and Biomedical technology Research center at NSLS-II LSBRP41GM111244 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI MCSWEENEY, SEAN · 2014 to 2018
$16.4M
Validating cholesterol-mediated Mycobacterium tuberculosis resistance to oxidative stress as a drug targetR01AI134054 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI SAMPSON, NICOLE S · 2017 to 2021
$2.0M
Canadian Institutes for Health ResearchNCI NIH HHS P30 CA008748NIAID NIH HHS R01 AI134054NIGMS NIH HHS P41 GM111244
6 · The paper itself

Abstract

Steroid-degrading bacteria, including

Indexed as

Acyl-CoA DehydrogenaseAcyl Coenzyme ABacterial ProteinsCholesterolCoenzyme ACoenzyme A LigasesMycobacterium tuberculosisSteroidsAcyl-CoA DehydrogenaseAcyl Coenzyme ABacterial ProteinsCholesterolCoenzyme ACoenzyme A LigasesSteroids

Identifiers

PMID32101684
PMCPMC7081610
OpenAlexW3007638541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.