Evidence map›Paper›PMID 32101612›Full record

ArticleThe Journal of nutrition2020

Dietary Supplement Use among Adult Cancer Survivors in the United States.

Mengxi Du, Hanqi Luo, Jeffrey B Blumberg, Gail Rogers, Fan Chen, Mengyuan Ruan, Zhilei Shan, Emily Biever, Fang Fang Zhang

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Dietary supplement use throughout the colorectal cancer disease trajectory: a prospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  8. Article
  9. Use of dietary supplements and over-the-counter products among adults with a self-reported history of cancer in Poland.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  10. Article
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  12. Review
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  15. Article
  16. Integrating Botanicals into Oncology Care: Consideration of FDA Regulation of Botanical Products and Botanical Clinical Trials.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Article
  17. Approaches to management of endocrine therapy-induced alopecia in breast cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Review
  18. Article
  19. Article
  20. Supplement use and its impact on daily life of cancer patients: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mengxi DuFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Hanqi LuoDepartment of Nutrition and Institute for Global Nutrition, University of California, Davis, Davis, CA, USA.
Jeffrey B BlumbergFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Gail RogersFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Fan ChenFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Mengyuan RuanFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Zhilei ShanFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Emily BieverNutrition Department, Dana Farber/Brigham and Women's Cancer Center, Boston, MA, USA.
Fang Fang ZhangFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Tufts University · USDana-Farber Brigham Cancer Center · USHebrew SeniorLife · USUniversity of California, Davis · US

Funding

Comparative and Cost-Effectiveness of Population Strategies to Improve Diet and Reduce CancerR01MD011501 · NIMHD · TUFTS UNIVERSITY BOSTON · PI ZHANG, FANG FANG · 2016 to 2019
$2.0M
NIMHD NIH HHS R01 MD011501
6 · The paper itself

Abstract

backgroundMany cancer patients initiate dietary supplement use after cancer diagnosis. How dietary supplement use contributes to the total nutrient intake among cancer survivors as compared with individuals without cancer needs to be determined.

objectivesWe aimed to evaluate nutrient intakes from dietary supplements among cancer survivors in relation to their total nutrient intake and compare those with individuals without cancer.

methodsWe evaluated the prevalence, dose, and reason for using dietary supplements among 2772 adult cancer survivors and 31,310 individuals without cancer who participated in the NHANES 2003-2016.

resultsCancer survivors reported a higher prevalence of any (70.4% vs. 51.2%) and multivitamin/mineral (48.9% vs. 36.6%) supplement use and supplement use of 11 individual vitamins and 8 minerals than individuals without cancer. Overall, cancer survivors had significantly higher amounts of nutrient intake from supplements but lower nutrient intakes from foods for the majority of the nutrients. Compared with individuals without cancer, cancer survivors had a higher percentage of individuals with inadequate intake (total nutrient intake <Estimated Average Requirement or Adequate Intake) for folate, vitamin B-6, niacin, calcium, copper, and phosphorus, due to lower intakes of these nutrients from foods. Cancer survivors also had a higher proportion of individuals with excess intake (total nutrient intake ≥Tolerable Upper Intake Level) for vitamin D, vitamin B-6, niacin, calcium, magnesium, and zinc, contributed by higher intakes of these nutrients from dietary supplements. Nearly half (46.1%) used dietary supplements on their own without consulting health care providers.

conclusionsCancer survivors reported a higher prevalence and dose of dietary supplement use but lower amounts of nutrient intake from foods than individuals without cancer. The inadequate nutrient intake from foods and the short-term and long-term health impact of dietary supplement use, especially at high doses, need to be further evaluated among cancer survivors.

Indexed as

Cancer SurvivorsDietary SupplementsDose-Response Relationship, DrugFemaleHumansLife StyleMaleMiddle AgedUnited Statescancer survivorsdietary supplement useexcess intakeinadequate intakenutrients

Identifiers

PMID32101612
PMCPMC7269731
OpenAlexW3008633723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.