Evidence map›Paper›PMID 32101460›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2020

Enhancement by TNF-α of TTX-resistant Na

Qin Li, Lu Qin, Jianhua Li

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Amplified P2XExperimental physiology · 2024
    Article
  5. Review
  6. Article
  7. KAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Effects of bradykinin on voltage-gated KThe Journal of physiology · 2021
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Qin LiHeart and Vascular Institute, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Lu QinHeart and Vascular Institute, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Jianhua LiHeart and Vascular Institute, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania.
Penn State Milton S. Hershey Medical Center · USPennsylvania State University · US

Funding

Project 3: Role Played by ASIC, P2X and EP4 Receptors in the Exercise Pressor Reflex in Health and Simulated PADP01HL134609 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KAUFMAN, MARC PETER · 2017 to 2021
$9.4M
Exercise pressor reflex in peripheral artery disease: beneficial effects of heating and mechanismsR01HL141198 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI CUI, JIAN, LI, JIANHUA · 2019 to 2023
$3.7M
NHLBI NIH HHS P01 HL134609NHLBI NIH HHS R01 HL141198
6 · The paper itself

Abstract

Femoral artery occlusion in rats has been used to study human peripheral artery disease (PAD). Using this animal model, a recent study suggests that increases in levels of tumor necrosis factor-α (TNF-α) and its receptor lead to exaggerated responses of sympathetic nervous activity and arterial blood pressure as metabolically sensitive muscle afferents are activated. Note that voltage-dependent Na

Indexed as

AnimalsFemoral ArteryGene Expression RegulationHindlimbMaleMuscle, SkeletalNAV1.8 Voltage-Gated Sodium ChannelRatsRats, Sprague-DawleySensory Receptor CellsSodium ChannelsTetrodotoxinTumor Necrosis Factor-alphaNAV1.8 Voltage-Gated Sodium ChannelScn10a protein, ratSodium ChannelsTetrodotoxinTumor Necrosis Factor-alphadorsal root ganglion neuronmuscle afferentNaV1.8 channelsperipheral artery diseaseTNF-α

Identifiers

PMID32101460
PMCPMC7191414
OpenAlexW3007786079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.