ArticleeLife2020
Experience shapes activity dynamics and stimulus coding of VIP inhibitory cells.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
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Who cites it
62 citing papers in PubMed, 116 citations in OpenAlex.
- Intrinsic timing, not temporal prediction, underlies ramping dynamics in visual and parietal cortex during passive behavior.Science advances · 2026Article
- Cell-Type-Specific Synaptic Scaling Mechanisms Differentially Contribute to Associative Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Disinhibitory signaling enables flexible coding of top-down information in cortical networks.PLoS biology · 2026Article
- Experience shapes the transformation of olfactory representations along the cortico-hippocampal pathway.eLife · 2026Article
- Ontology-constrained multi-LLM scoring of hypothesis support in the predictive processing literature.Research square · 2026Article
- Orbitofrontal cortex drives predictive filtering of sensory responses.Nature neuroscience · 2026Article
- Environmental enrichment accelerates the stabilization of cortical representation duringiScience · 2026Article
- Higher-level spatial prediction in natural vision across mouse visual cortex.PLoS computational biology · 2026Article
- Constructing biologically constrained RNNs via Dale's backpropagation and topologically informed pruning.Science advances · 2025Article
- Mouse Hippocampal Sharp-Wave Ripple Dataset Curated From Public Neuropixels Datasets.Scientific data · 2025Article
- Environmental Novelty Modulates Rapid Cortical Plasticity During Navigation.bioRxiv : the preprint server for biology · 2025Article
- Map of spiking activity underlying change detection in the mouse visual system.bioRxiv : the preprint server for biology · 2025Article
- Exploring the Architectural Biases of the Cortical Microcircuit.Neural computation · 2025Article
- Environmental enrichment accelerates cortical memory consolidation.bioRxiv : the preprint server for biology · 2025Article
- Selective engagement of prefrontal VIP neurons in reversal learning.Science advances · 2025Article
- Learning predictive signals within a local recurrent circuit.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Predictive coding: a more cognitive process than we thought?Trends in cognitive sciences · 2025Review
- State modulation in spatial networks with three interneuron subtypes.Science advances · 2025Article
- Diversity of omission responses to visual images across brain-wide regions.Science advances · 2025Article
- Integrating multimodal data to understand cortical circuit architecture and function.Nature neuroscience · 2025Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 1 institution in 1 country.
Funding
Abstract
Cortical circuits can flexibly change with experience and learning, but the effects on specific cell types, including distinct inhibitory types, are not well understood. Here we investigated how excitatory and VIP inhibitory cells in layer 2/3 of mouse visual cortex were impacted by visual experience in the context of a behavioral task. Mice learned a visual change detection task with a set of eight natural scene images. Subsequently, during 2-photon imaging experiments, mice performed the task with these familiar images and three sets of novel images. Strikingly, the temporal dynamics of VIP activity differed markedly between novel and familiar images: VIP cells were stimulus-driven by novel images but were suppressed by familiar stimuli and showed ramping activity when expected stimuli were omitted from a temporally predictable sequence. This prominent change in VIP activity suggests that these cells may adopt different modes of processing under novel versus familiar conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.