Evidence map›Paper›PMID 32101148›Full record

ArticleBMC gastroenterology2020

Diagnostic efficacy of double-balloon enteroscopy in patients with suspected isolated small bowel Crohn's disease.

Zihan Huang, Xiang Liu, Fei Yang, Guoxin Wang, Nan Ge, Sheng Wang, Jintao Guo, Siyu Sun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zihan HuangThe Department of Gastroenterology, Shengjing Hospital, China Medical University, No.36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
Xiang LiuThe Department of Gastroenterology, Shengjing Hospital, China Medical University, No.36, Sanhao Street, Shenyang, 110004, Liaoning Province, China. liux@sj-hospital.org.
Fei YangThe Department of Gastroenterology, Shengjing Hospital, China Medical University, No.36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
Guoxin WangThe Department of Gastroenterology, Shengjing Hospital, China Medical University, No.36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
Nan GeThe Department of Gastroenterology, Shengjing Hospital, China Medical University, No.36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
Sheng WangThe Department of Gastroenterology, Shengjing Hospital, China Medical University, No.36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
Jintao GuoThe Department of Gastroenterology, Shengjing Hospital, China Medical University, No.36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
Siyu SunThe Department of Gastroenterology, Shengjing Hospital, China Medical University, No.36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
China Medical University · CN

Funding

Shenyang Science and Technology Bureau F16-206-9-38
6 · The paper itself

Abstract

backgroundOwing to the development of double-balloon enteroscopy (DBE) and video capsule endoscopy (VCE) in recent years, direct visualization of the entire small intestinal mucosa has become possible. Because of the nonspecific symptoms and the anatomic location of the small bowel, diagnosis of isolated small bowel Crohn's disease (CD) remains a challenge. The aim of this research was to explore the value of DBE for isolated small bowel CD in situations where routine tests cannot confirm the diagnosis.

methodsThis study included patients with suspected isolated small bowel CD who were hospitalized in Shengjing Hospital from April 2014 to June 2018. We included patients presenting with chronic diarrhea, abdominal pain, abdominal mass, perianal lesions, and systemic symptoms including weight loss, fever, and anemia after excluding infection factors. Patients with purely colonic CD were excluded from this cohort. Patients with suspected isolated small bowel CD underwent DBE.

resultsIn 16/18 patients, pathological findings were detected by DBE. In 12 of the cases, small bowel CD was confirmed. The remaining four patients were diagnosed with small bowel inflammation, duodenal carcinoma, ileum inflammation and small bowel ulcers. However, the diagnosis of CD was confirmed in 14/18 (78%) patients by taking into account the clinical presentation, endoscopic and histological results as well as the experimental treatment. DBE assisted in the diagnosis in 86% (12/14) of the patients.

conclusionsIn the diagnosis of small bowel CD, DBE is a helpful tool. Before assessment with DBE, clinical features, colonoscopy, and CT were used to initially assess the intestine. According to the lesions indicated by CT, we chose the most appropriate endoscope insertion route, and combined the endoscopic characteristics and pathological results of DBE to confirm the diagnosis.

Indexed as

Double-Balloon EnteroscopyAdolescentAdultAgedCapsule EndoscopyColonoscopyCrohn DiseaseDuodenal NeoplasmsEnteritisFemaleHumansIleumIntestinal MucosaIntestine, SmallMaleMiddle AgedCrohn’s diseaseDouble-balloon enteroscopyInflammatory bowel diseaseSmall bowel

Identifiers

PMID32101148
PMCPMC7045397
OpenAlexW3012706663

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.