Evidence map›Paper›PMID 32101139›Full record

ArticleBMC biology2020

Ca

Beáta Lizák, Julia Birk, Melinda Zana, Gergely Kosztyi, Denise V Kratschmar, Alex Odermatt, Richard Zimmermann, Miklós Geiszt, Christian Appenzeller-Herzog, Gábor Bánhegyi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. CaBMC biology · 2020
    Article
  14. Intracellular CaFrontiers in cell and developmental biology · 2020
    Review
  15. The Two-Way Relationship Between Calcium and Metabolism in Cancer.Frontiers in cell and developmental biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Beáta LizákDepartment of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary. lizak.beata@med.semmelweis-univ.hu.ORCID 0000-0001-9840-4836
Julia BirkDivision of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Melinda ZanaDepartment of Physiology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Gergely KosztyiDepartment of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary.
Denise V KratschmarDivision of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Alex OdermattDivision of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.
Richard ZimmermannMedical Biochemistry and Molecular Biology, Saarland University, 66421, Homburg, Germany.
Miklós GeisztDepartment of Physiology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Christian Appenzeller-HerzogDivision of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland. christian.appenzeller@unibas.ch.
Gábor BánhegyiDepartment of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary.
Semmelweis University · HUUniversity of Basel · CHSaarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe lumen of the endoplasmic reticulum (ER) acts as a cellular Ca

resultsWe found that Ca

conclusionsOur data strongly suggest that ER influx of cytosolic GSH, rather than inhibition of local oxidoreductases, is responsible for the reductive shift upon Ca

Indexed as

CalciumCalreticulinCytosolEndoplasmic ReticulumGlutathioneHumansProtein BindingCalciumCalreticulinCALR protein, humanGlutathioneCalciumCalreticulinCyclophilinsCyclosporine AEndoplasmic reticulumEndoplasmic reticulum stressGlutathioneMembrane transport proteinsRedox homeostasisSec61 translocon

Identifiers

PMID32101139
PMCPMC7043043
OpenAlexW3012842293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.