ArticleJournal of medical virology2020
Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection.
Article in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 579 papers, 10 of them syntheses that pooled it.
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Who cites it
579 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Extrapulmonary manifestations and complications of severe acute respiratory syndrome coronavirus-2 infection: a systematic review.Singapore medical journal · 2023Pooled it
- Neurological and Head/Eyes/Ears/Nose/Throat Manifestations of COVID-19: A Systematic Review and Meta-Analysis.The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2022Pooled it
- Different rates of conjunctivitis in COVID-19 eastern and western hospitalized patients: a meta-analysis.Internal and emergency medicine · 2022Pooled it
- Ocular transmission and manifestation for coronavirus disease: a systematic review.International health · 2022Pooled it
- COVID-19-Related Retinal Micro-vasculopathy - A Review of Current Evidence.American journal of ophthalmology · 2022Pooled it
- Clinical and laboratory findings of COVID-19: A systematic review and meta-analysis.Journal of the Formosan Medical Association = Taiwan yi zhi · 2021Pooled it
- Detection of three pandemic causing coronaviruses from non-respiratory samples: systematic review and meta-analysis.Scientific reports · 2021Pooled it
- Ophthalmology-focused publications and findings on COVID-19: A systematic review.European journal of ophthalmology · 2021Pooled it
- An Eye on COVID-19: A Meta-analysis of Positive Conjunctival Reverse Transcriptase-Polymerase Chain Reaction and SARS-CoV-2 Conjunctivitis Prevalence.Optometry and vision science : official publication of the American Academy of Optometry · 2021Pooled it
- A systematic review on the recurrence of SARS-CoV-2 virus: frequency, risk factors, and possible explanations.Infectious diseases (London, England) · 2021Pooled it
- Intraocular pressure modulation with thermal stimuli.Arquivos brasileiros de oftalmologia · 2024Trial
- Comparison of optic nerve head and macular perfusion changes before and after the development of COVID-19.BMC ophthalmology · 2026Article
- Time-series analysis of pollen concentration effects on allergic conjunctivitis healthcare visits in Beijing, 2023-2024.Frontiers in public health · 2026Article
- Intravitreal exposure to the SARS-CoV-2 spike protein is associated with aggravated retinal lesions in a murine model of central retinal vein occlusion.Frontiers in medicine · 2026Article
- External Ocular Manifestations among Patients Diagnosed with Coronavirus Disease 2019 in a Referral Center in the Philippines.Acta medica Philippina · 2026Article
- The Effects of the COVID-19 Pandemic on the Follow-Up of Patients with Age-Related Macular Degeneration in a Tertiary Hospital in London, the UK.Journal of clinical medicine · 2025Article
- Optical Coherence Tomography (OCT) Findings in Post-COVID-19 Healthcare Workers.Journal of imaging · 2025Article
- The influence of SARS-CoV-2 spike protein exposure on retinal development in the human retinal organoids.Cell & bioscience · 2025Article
- Continued changes to contact lens practice following adjustments made as a result of the COVID-19 pandemic.Heliyon · 2025Article
- Analyzing the characteristics of Otitis media with effusion following SARS-CoV-2 infection in China.Frontiers in surgery · 2025Article
519 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to assess the presence of novel coronavirus in tears and conjunctival secretions of SARS-CoV-2-infected patients.
methodsA prospective interventional case series study was performed, and 30 confirmed novel coronavirus pneumonia (NCP) patients were selected at the First Affiliated Hospital of Zhejiang University from 26 January 2020 to 9 February 2020. At an interval of 2 to 3 days, tear and conjunctival secretions were collected twice with disposable sampling swabs for reverse-transcription polymerase chain reaction (RT-PCR) assay.
resultsTwenty-one common-type and nine severe-type NCP patients were enrolled. Two samples of tear and conjunctival secretions were obtained from the only one patient with conjunctivitis yielded positive RT-PCR results. Fifty-eight samples from other patents were all negative.
conclusionWe speculate that SARS-CoV-2 may be detected in the tears and conjunctival secretions in NCP patients with conjunctivitis.
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