ArticleAging2020
Subjective cognitive decline detected by the oscillatory connectivity in the default mode network: a magnetoencephalographic study.
Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
- Baseline predictors of neurophysiological response to combined physical and cognitive training in older adults with subjective cognitive decline.BMC geriatrics · 2026Trial
- Effects of 6-Month Combined Physical Exercise and Cognitive Training on Neuropsychological and Neurophysiological Function in Older Adults with Subjective Cognitive Decline: A Randomized Controlled Trial.Journal of Alzheimer's disease : JAD · 2024Trial
- Preoperative MEG reveals differential brain network characteristics in drug-resistant epilepsy patients based on vagus nerve stimulation response.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Memory Test Performance of People with Subjective Cognitive Decline Recruited From Different Settings: A Systematic Review and Meta-analysis.Neuropsychology review · 2025Review
- Temporal stability and neural complexity in resting-state MEG predict migraine phenotypes.The journal of headache and pain · 2025Article
- Clinical definition, biological characterization, and detection guidelines of subjective cognitive decline due to Alzheimer's disease and related dementia: A position paper from ISTAART SCD PIA.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Distributions and network changes of brain activity in the acute phase of anti-NMDAR encephalitis: a MEG study.Journal of neurology · 2025Article
- Altered neuromagnetic activity under visual stimuli in migraine: a multi-frequency magnetoencephalography study.Frontiers in neurology · 2025Article
- Neurophysiological markers of early cognitive decline in older adults: a mini-review of electroencephalography studies for precursors of dementia.Frontiers in aging neuroscience · 2024Review
- Hyperbolic graph embedding of MEG brain networks to study brain alterations in individuals with subjective cognitive decline.bioRxiv : the preprint server for biology · 2023Article
- Shared alterations in hippocampal structural covariance in subjective cognitive decline and migraine.Frontiers in aging neuroscience · 2023Article
- Altered neuromagnetic activity in default mode network in childhood absence epilepsy.Frontiers in neuroscience · 2023Article
- Frequency-specific alterations in intrinsic low-frequency oscillations in newly diagnosed male patients with obstructive sleep apnea.Frontiers in neuroscience · 2022Article
- Reduced Inter-Voxel White Matter Integrity in Subjective Cognitive Decline: Diffusion Tensor Imaging With Tract-Based Spatial Statistics Analysis.Frontiers in aging neuroscience · 2022Article
- Alterations in the default mode network in rolandic epilepsy with mild spike-wave index in non-rapid eye movement sleep.Frontiers in neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Discriminating between those with and without subjective cognitive decline (SCD) in cross-sectional investigations using neuropsychological tests is challenging. The available magnetoencephalographic (MEG) studies have demonstrated altered alpha-band spectral power and functional connectivity in those with SCD. However, whether the functional connectivity in other frequencies and brain networks, particularly the default mode network (DMN), exhibits abnormalities in SCD remains poorly understood. We recruited 26 healthy controls (HC) without SCD and 27 individuals with SCD to perform resting-state MEG recordings. The power of each frequency band and functional connectivity within the DMN were compared between these two groups. Posterior cingulate cortex (PCC)-based connectivity was also used to test its diagnostic accuracy as a predictor of SCD. There were no significant between-group differences of spectral power in the regional nodes. However, compared with HC, those with SCD demonstrated increased delta-band and gamma-band functional connectivity within the DMN. Moreover, node strength in the PCC exhibited a good discrimination ability at both delta and gamma frequencies. Our data suggest that the node strength of delta and gamma frequencies in the PCC may be a good neurophysiological marker in the discrimination of individuals with SCD from those without SCD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.