Evidence map›Paper›PMID 32100186›Full record

ReviewCellular and molecular neurobiology2020

The Role of the Spinal Wnt Signaling Pathway in HIV-Related Neuropathic Pain.

Jian Huang, Chris Bloe Bloe, Xinxin Zhou, Shengjun Wu, Wenping Zhang

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Neuropathic pain; what we know and what we should do about it.Frontiers in pain research (Lausanne, Switzerland) · 2023
    Review
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jian HuangZhejiang Provincial Key Laboratory of Silkworm Bioreactor and Biomedicine, College of Life Science and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.ORCID https://orcid.org/0000-0003-2693-2693
Chris Bloe BloeZhejiang Provincial Key Laboratory of Silkworm Bioreactor and Biomedicine, College of Life Science and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.ORCID https://orcid.org/0000-0003-4081-8707
Xinxin ZhouZhejiang Provincial Key Laboratory of Silkworm Bioreactor and Biomedicine, College of Life Science and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.ORCID https://orcid.org/0000-0002-0288-3412
Shengjun WuClinical Laboratory of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China. 3202107@zju.edu.cn.ORCID https://orcid.org/0000-0003-2526-0696
Wenping ZhangZhejiang Provincial Key Laboratory of Silkworm Bioreactor and Biomedicine, College of Life Science and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China. wenpingzhang@zstu.edu.cn.ORCID http://orcid.org/0000-0002-3107-8965
Zhejiang Sci-Tech University · CNSir Run Run Shaw Hospital · CN

Funding

Health Commission of Zhejiang Province 2018244788Natural Science Foundation of Zhejiang Province LY19H090029
6 · The paper itself

Abstract

Human immunodeficiency virus (HIV)-related neuropathic pain includes HIV-induced neuropathic pain (HNP) and antiretroviral therapy-induced neuropathic pain (ART-NP). A significant amount of evidence from the past few years has shown that the development of HIV-related neuropathic pain is closely related to the activation of the Wnt signaling pathway in the spinal cord. This review summarizes the function of the spinal Wnt signaling pathway in HIV-induced neuropathic pain, focusing on the role of the spinal Wnt signaling pathway in HNP, and provides a theoretical basis for further studies and the exploration of new target drugs.

Indexed as

AnimalsDisease Models, AnimalDrug DevelopmentHIV InfectionsHumansNeuralgiaSpinal CordWnt Signaling PathwayHuman immunodeficiency virusNeuropathic painSomatosensorySpinal cordWnt signaling pathway

Identifiers

PMID32100186
PMCPMC11448846
OpenAlexW3006820596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.