ArticleEuropean journal of epidemiology2020
Lifelines NEXT: a prospective birth cohort adding the next generation to the three-generation Lifelines cohort study.
Article in European journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome.Cell host & microbe · 2024Trial
- Extensive genomic diversity in Desulfovibrio reveals species-specific functional traits associated with disease.Nature communications · 2026Article
- Article
- Maternal secretor status and human milk oligosaccharides influence the infant gut resistome.Cell reports. Medicine · 2026Article
- Metabolomics and Human Health: Progress, Insights, Challenges and the Concept of a Healthy Metabolome.Biomolecules · 2026Review
- Prenatal androgen exposure delays puberty onset in female offspring rats: possible roles of leptin and α-MSH.Endocrine · 2025Article
- Negativeome characterization and decontamination in early-life virome studies.Nature communications · 2025Article
- Low-cost generation of clinical-grade, layperson-friendly pharmacogenetic passports using oligonucleotide arrays.American journal of human genetics · 2025Article
- Examining the healthy human microbiome concept.Nature reviews. Microbiology · 2025Review
- Maternal Nutrition, Toxicants, and Epigenetic Programming of Obesity Across Generations.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Review
- Integrating a life course perspective in work environment and health research: empirical challenges and interdisciplinary opportunities.Scandinavian journal of work, environment & health · 2024Article
- Transmission and dynamics of mother-infant gut viruses during pregnancy and early life.Nature communications · 2024Article
- The Women4Health cohort: a unique cohort to study women-specific mechanisms of cardio-metabolic regulation.European heart journal open · 2024Article
- Analysis of microbial composition and sharing in low-biomass human milk samples: a comparison of DNA isolation and sequencing techniques.ISME communications · 2023Article
- Semi-automatic translation of medicine usage data (in Dutch, free-text) from Lifelines COVID-19 questionnaires to ATC codes.Database : the journal of biological databases and curation · 2023Article
- Mechanism of leptin-NPY on the onset of puberty in male offspring rats after androgen intervention during pregnancy.Frontiers in endocrinology · 2023Article
- Cohort Profile Update: Lifelines, a three-generation cohort study and biobank.International journal of epidemiology · 2022Article
- Validation of a clinical and genetic model for predicting severe COVID-19.Epidemiology and infection · 2022Article
- Sex and Gender-Related Differences in COVID-19 Diagnoses and SARS-CoV-2 Testing Practices During the First Wave of the Pandemic: The Dutch Lifelines COVID-19 Cohort Study.Journal of women's health (2002) · 2021Article
- Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort.BMJ open · 2021Article
Corrections and comments
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
Abstract
Epidemiological research has shown there to be a strong relationship between preconceptional, prenatal, birth and early-life factors and lifelong health. The Lifelines NEXT is a birth cohort designed to study the effects of intrinsic and extrinsic determinants on health and disease in a four-generation design. It is embedded within the Lifelines cohort study, a prospective three-generation population-based cohort study recording the health and health-related aspects of 167,729 individuals living in Northern Netherlands. In Lifelines NEXT we aim to include 1500 pregnant Lifelines participants and intensively follow them, their partners and their children until at least 1 year after birth. Longer-term follow-up of physical and psychological health will then be embedded following Lifelines procedures. During the Lifelines NEXT study period biomaterials-including maternal and neonatal (cord) blood, placental tissue, feces, breast milk, nasal swabs and urine-will be collected from the mother and child at 10 time points. We will also collect data on medical, social, lifestyle and environmental factors via questionnaires at 14 different time points and continuous data via connected devices. The extensive collection of different (bio)materials from mother and child during pregnancy and afterwards will provide the means to relate environmental factors including maternal and neonatal microbiome composition) to (epi)genetics, health and developmental outcomes. The nesting of the study within Lifelines enables us to include preconceptional transgenerational data and can be used to identify other extended families within the cohort.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.