Evidence map›Paper›PMID 32100118›Full record

ArticleJournal of anesthesia2020

The effect of desflurane on retinal angiogenesis in a mouse model of oxygen-induced retinopathy.

Hyun-Su Ri, Sun Sik Bae, Jung Min Ha, Hee Young Kim, Seung-Hoon Baek

Abstract read
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Article in Journal of anesthesia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hyun-Su RiDepartment of Anesthesia and Pain Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Geumo-ro 20, Yangsan, 50612, Republic of Korea.
Sun Sik BaeDepartment of Pharmacology, Gene and Cell Therapy Center for Vessel-Associated Disease, Medical Research Institute, Pusan National University School of Medicine, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.
Jung Min HaDepartment of Pharmacology, Gene and Cell Therapy Center for Vessel-Associated Disease, Medical Research Institute, Pusan National University School of Medicine, Busandaehak-ro 49, Mulgeum-eup, Yangsan, 50612, Republic of Korea.
Hee Young KimDepartment of Anesthesia and Pain Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Geumo-ro 20, Yangsan, 50612, Republic of Korea.
Seung-Hoon BaekDepartment of Anesthesia and Pain Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Geumo-ro 20, Yangsan, 50612, Republic of Korea. md.baeksh@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRetinopathy of prematurity (ROP) is an ocular disorder that primarily occurs in premature infants and is the most common cause of vision impairment. This study examined the effect of desflurane on angiogenesis in a mouse model of oxygen-induced retinopathy (OIR).

methodsMice were randomly allocated to the control (C), ROP control (R

resultsThe ratio of avascular area/total retinal area was not changed significantly in the R

conclusionsDesflurane does not have a significant influence on retinal angiogenesis via HIF-1α and VEGF-A expression in the OIR mouse model. However, these findings are not directly applicable to premature infants, and it is thus necessary to perform further studies to determine the effect of desflurane on angiogenesis.

Indexed as

OxygenRetinal NeovascularizationAnimalsAnimals, NewbornDesfluraneDisease Models, AnimalHumansInfant, NewbornMiceMice, Inbred C57BLRetinaVascular Endothelial Growth Factor ADesfluraneOxygenVascular Endothelial Growth Factor AAngiogenesisDesfluraneRetinopathy of prematurityVascular endothelial growth factor

Identifiers

PMID32100118

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.