Evidence map›Paper›PMID 32100063›Full record

ArticleWorld journal of surgery2020

Efficacy of Microwave Ablation in the Treatment of Large (≥3 cm) Benign Thyroid Nodules.

Huynh Quang Khanh, Ngo Quoc Hung, Vu Huu Vinh, Nguyen Van Khoi, Nguyen Lam Vuong

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Huynh Quang KhanhDepartment of Thoracic Surgery, Cho Ray Hospital, 201B Nguyen Chi Thanh, Ward 12, District 5, Ho Chi Minh City, Viet Nam.
Ngo Quoc HungDepartment of Thoracic Surgery, Cho Ray Hospital, 201B Nguyen Chi Thanh, Ward 12, District 5, Ho Chi Minh City, Viet Nam.
Vu Huu VinhDepartment of Thoracic Surgery, Cho Ray Hospital, 201B Nguyen Chi Thanh, Ward 12, District 5, Ho Chi Minh City, Viet Nam.
Nguyen Van KhoiDepartment of Thoracic Surgery, Cho Ray Hospital, 201B Nguyen Chi Thanh, Ward 12, District 5, Ho Chi Minh City, Viet Nam.
Nguyen Lam VuongDepartment of Cardiovascular and Thoracic Surgery, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, 217 Hong Bang, Ward 11, District 5, Ho Chi Minh City, Viet Nam. nguyenlamvuong@ump.edu.vn.ORCID http://orcid.org/0000-0003-2684-3041
Cho Ray Hospital · VNUniversity of Medicine and Pharmacy at Ho Chi Minh City · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLarge (≥3 cm) benign thyroid nodules usually cause clinical symptoms or cosmetic concerns and therefore require treatment. Microwave ablation (MWA) is a potential valid non-surgical treatment alternative, but there is a lack of evidence. Thus, this study is to evaluate the safety and efficacy of MWA in the treatment of large benign thyroid nodules.

methodsA retrospective study was conducted on 42 large benign thyroid nodules in 40 patients treated with MWA. We used the trans-isthmic approach and moving-shot technique to perform the procedure under ultrasound (US) guidance. Patients were followed by clinical and US examinations at 1, 3, 6, and 12 months after the MWA. Study outcomes were complications, volume reduction ratio (VRR), symptom and cosmetic scores, and the requirement of multiple MWA sessions.

resultsThere were 31 females and 9 males, with a median age of 46 years. The medians of largest diameter and volume of the nodules were 40 mm and 22 ml. Four (10%) minor complications were observed. The mean VRR was 75.1, 85.2, and 96.4% after 3, 6, and 12 months. The mean symptom and cosmetic scores dropped from 8.0 and 3.8 (before treatment) to 2.8 and 2.3 (at 12 months), respectively. Thirteen nodules (31%) required two MWA sessions.

conclusionsMWA is safe, effective, and can be a good option to treat large benign thyroid nodules. More studies with large dataset and long follow-up are required to improve its safety and efficacy.

Indexed as

Ablation TechniquesAdultFemaleFollow-Up StudiesHumansMaleMicrowavesMiddle AgedRetrospective StudiesThyroid NoduleTreatment OutcomeUltrasonography, Interventional

Identifiers

PMID32100063
OpenAlexW3008241407

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.