Evidence map›Paper›PMID 32099974›Full record

ArticleJournal of life sciences (Westlake Village, Calif.)2019

The Emerging Role of Mitophagy in Kidney Diseases.

Divya Bhatia, Mary E Choi

Open access · greenAbstract read
In one paragraph

Article in Journal of life sciences (Westlake Village, Calif.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Article
  3. Autophagy: a double-edged sword in ischemia-reperfusion injury.Cellular & molecular biology letters · 2025
    Review
  4. Article
  5. Mitophagy Regulates Kidney Diseases.Kidney diseases (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Kidney Aging and Chronic Kidney Disease.International journal of molecular sciences · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Divya BhatiaDivision of Nephrology and Hypertension, Joan and Sanford I. Weill Department of Medicine, NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, NY, USA.
Mary E ChoiDivision of Nephrology and Hypertension, Joan and Sanford I. Weill Department of Medicine, NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, NY, USA.
Cornell University · US

Funding

Metabolic dysfunction regulates mitophagy-dependent necroptosis in COPDR01HL132198 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHOI, AUGUSTINE M, CHOI, MARY E · 2017 to 2020
$2.2M
Novel role of RIPK3-dependent necroptosis pathway in lung and kidney fibrosisR01HL133801 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHOI, AUGUSTINE M, CHOI, MARY E · 2017 to 2020
$2.1M
NHLBI NIH HHS R01 HL132198NHLBI NIH HHS R01 HL133801
6 · The paper itself

Abstract

Mitochondria fulfill the high metabolic energy demands of the kidney and are regularly exposed to oxidative stress causing mitochondrial damage. The selective removal of damaged and dysfunctional mitochondria through a process known as mitophagy is essential in maintaining cellular homeostasis and physiological function. Mitochondrial quality control by mitophagy is particularly crucial for an organ such as the kidney, which is rich in mitochondria. The role of mitophagy in the pathogenesis of kidney diseases has lately gained significant attention. In this review, we summarize the current understanding of the implications of mitophagy during pathological conditions of the kidney, including acute and chronic kidney diseases.

Indexed as

acute kidney injurychronic kidney diseasemitochondriaMitophagyoxidative stress

Identifiers

PMID32099974
PMCPMC7041910
OpenAlexW2999810171

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.