ArticleJournal of the Endocrine Society2020
Tracking of Serum DHEAS Concentrations from Age 1 to 6 Years: A Prospective Cohort Study.
Article in Journal of the Endocrine Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- The association between birth weight/rapid weight gain and early menarche: a systematic review and meta-analysis based on cohort studies.BMC pediatrics · 2025Pooled it
- A rise in prepubertal DHEA in the spiny mouse reveals the effect of adrenarche on the reproductive axis.BMC biology · 2026Article
- Adrenarche as a regulator of sensitivity to early adversity.Journal of neuroendocrinology · 2026Review
- Predicted Adult Height Remained Normal in Children With Premature Adrenarche Despite Advanced Bone Age.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Association of childhood dehydroepiandrosterone sulfate concentration, pubertal development, and DNA methylation at puberty-related genes.European journal of endocrinology · 2024Article
- Accelerated Early Childhood Growth Is Associated With the Development of Earlier Adrenarche and Puberty.Journal of the Endocrine Society · 2024Article
- Association of dehydroepiandrosterone sulfate, birth size, adiposity and cardiometabolic risk factors in 7-year-old children.Pediatric research · 2022Article
- Congenital Hypothyroidism and Hyperthyroidism Alters Adrenal Gene Expression, Development, and Function.Thyroid : official journal of the American Thyroid Association · 2022Article
- Analysis of Early-Life Growth and Age at Pubertal Onset in US Children.JAMA network open · 2022Article
- The Enigma of the Adrenarche: Identifying the Early Life Mechanisms and Possible Role in Postnatal Brain Development.International journal of molecular sciences · 2021Review
- Update on adrenarche.Current opinion in pediatrics · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextAdrenarche is a gradual process, but its programming is unknown.
objectiveThe objective of this article is to examine the trajectory of dehydroepiandrosterone sulfate (DHEAS) from age 1 to 6 years and the associations of early growth with DHEAS concentration by age 6 years. DESIGN AND
participantsLongitudinal data from a population sample of 78 children (43 girls) with serum samples for DHEAS and insulin-like growth factor 1 (IGF-1) measurements available at ages 1 and 6 years.
main outcome measureSerum DHEAS concentration at age 6 years.
resultsDHEAS concentration at age 1 year correlated with DHEAS concentration at age 6 years (r = 0.594,
conclusionsHigher serum DHEAS concentrations already at age 1 year are associated with those at age 6 years. Also, shorter birth length and rapid catch-up growth in length by age 1 year are associated with higher DHEAS concentrations at age 6 years. These results corroborate the early origin of adrenarche and strongly suggest that part of adrenarchal programming already takes place by the end of infancy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.