Evidence map›Paper›PMID 32099945›Full record

ArticleJournal of the Endocrine Society2020

Jinjiang Fan, Enrico Campioli, Chantal Sottas, Barry Zirkin, Vassilios Papadopoulos

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Cholesterol-dependent enzyme activity of human TSPO1.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Review
  3. Frontiers in veterinary science · 2025
    Article
  4. Article
  5. Review
  6. Steroidogenic factor 1 (SF-1;Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. TSPO protein binding partners in bacteria, animals, and plants.Journal of bioenergetics and biomembranes · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Journal of the Endocrine Society · 2020
    Article
  16. Commentary:Frontiers in endocrinology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jinjiang FanThe Research Institute of the McGill University Health Centre.
Enrico CampioliThe Research Institute of the McGill University Health Centre.
Chantal SottasDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, California, US.
Barry ZirkinDepartment of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, US.
Vassilios PapadopoulosThe Research Institute of the McGill University Health Centre.ORCID 0000-0002-1183-8568
McGill University Health Centre · CAUniversity of Southern California · USJohns Hopkins University · US

Funding

AGING AND LEYDIG CELL FUNCTIONR01AG021092 · NIA · JOHNS HOPKINS UNIVERSITY · PI ZIRKIN, BARRY R · 2002 to 2019
$3.1M
NIA NIH HHS R01 AG021092
6 · The paper itself

Abstract

Although the role of translocator protein (TSPO) in cholesterol transport in steroid-synthesizing cells has been studied extensively, recent studies of TSPO genetic depletion have questioned its role.

Indexed as

autophagycholesteryl esterscompensatory genetic networkgenetic linkageglobal knockoutsteroidtestosteronetranslocator protein

Identifiers

PMID32099945
PMCPMC7031085
OpenAlexW2999578652

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.