Evidence map›Paper›PMID 32099765›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020

Neural and Psychological Predictors of Cognitive Enhancement and Impairment from Neurostimulation.

Li-Zhuang Yang, Wei Zhang, Wenjuan Wang, Zhiyu Yang, Hongzhi Wang, Zhi-De Deng, Chuanfu Li, Bensheng Qiu, Da-Ren Zhang, Roi Cohen Kadosh and 2 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

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  5. Review
  6. Never-Ending Learning for Explainable Brain Computing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Li-Zhuang YangAnhui Province Key Laboratory of Medical Physics and Technology Center of Medical Physics and Technology Hefei Institutes of Physical Science Chinese Academy of Sciences Hefei Anhui 230031 China.ORCID https://orcid.org/0000-0002-0192-4323
Wei ZhangHefei National Laboratory for Physical Sciences at the Microscale, and School of Life Sciences University of Science and Technology of China Hefei Anhui 230027 China.
Wenjuan WangHefei National Laboratory for Physical Sciences at the Microscale, and School of Life Sciences University of Science and Technology of China Hefei Anhui 230027 China.
Zhiyu YangHefei National Laboratory for Physical Sciences at the Microscale, and School of Life Sciences University of Science and Technology of China Hefei Anhui 230027 China.
Hongzhi WangAnhui Province Key Laboratory of Medical Physics and Technology Center of Medical Physics and Technology Hefei Institutes of Physical Science Chinese Academy of Sciences Hefei Anhui 230031 China.
Zhi-De DengNoninvasive Neuromodulation Unit Experimental Therapeutics & Pathophysiology Branch Intramural Research Program National Institute of Mental Health National Institutes of Health Bethesda MD 20892-9663 USA.
Chuanfu LiLaboratory of Digital Medical Imaging Medical Imaging Center First Affiliated Hospital Anhui University of Chinese Medicine Hefei Anhui 230031 China.
Bensheng QiuCenter for Biomedical Engineering University of Science and Technology of China Hefei Anhui 230027 China.
Da-Ren ZhangHefei National Laboratory for Physical Sciences at the Microscale, and School of Life Sciences University of Science and Technology of China Hefei Anhui 230027 China.
Roi Cohen KadoshDepartment of Experimental Psychology University of Oxford Oxford OX1 3UD UK.
Hai LiAnhui Province Key Laboratory of Medical Physics and Technology Center of Medical Physics and Technology Hefei Institutes of Physical Science Chinese Academy of Sciences Hefei Anhui 230031 China.
Xiaochu ZhangHefei National Laboratory for Physical Sciences at the Microscale, and School of Life Sciences University of Science and Technology of China Hefei Anhui 230027 China.ORCID https://orcid.org/0000-0002-7541-0130
University of Science and Technology of China · CNChinese Academy of Sciences · CNAnhui Medical University · CNNational Institutes of Health · USUniversity of Oxford · GB

Funding

Non-invasive Neuromodulation Unit (NNU)ZIAMH002955 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI ZARATE, CARLOS · 2016 to 2025
$40.3M
Intramural NIH HHS ZIA MH002955
6 · The paper itself

Abstract

Modulating the temporoparietal junction (TPJ), especially the right counterpart, shows promises in enhancing social cognitive ability. However, it is ambiguous whether the functional lateralization of TPJ determines people's responsiveness to brain stimulation. Here, this issue is investigated with an individual difference approach. Forty-five participants attended three sessions of transcranial direct current stimulation (tDCS) experiments and one neuroimaging session. The results support the symmetric mechanism of left and right TPJ stimulation. First, the left and right TPJ stimulation effect are comparable in the group-level analysis. Second, the individual-level analysis reveals that a less right-lateralized TPJ is associated with a higher level of responsiveness. Participants could be classified into positive responders showing cognitive enhancement and negative responders showing cognitive impairment due to stimulation. The positive responders show weaker connectivity between bilateral TPJ and the medial prefrontal cortex, which mediates the prediction of offline responsiveness by the lateralization and the social-related trait. These findings call for a better characterization and predictive models for whom tDCS should be used for, and highlight the necessity and feasibility of prestimulation screening.

Indexed as

lateralizationmedial superior frontal gyrusneurostimulationtDCStemporoparietal junction

Identifiers

PMID32099765
PMCPMC7029648
OpenAlexW2990468196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.