Evidence map›Paper›PMID 32099582›Full record

ReviewCardiovascular therapeutics2019

Burden of Coronary Artery Disease and Peripheral Artery Disease: A Literature Review.

Rupert Bauersachs, Uwe Zeymer, Jean-Baptiste Brière, Caroline Marre, Kevin Bowrin, Maria Huelsebeck

2 registry-linked trialsOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cardiovascular therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 208 papers, 19 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
208citing papers in PubMed, 19 pooled it
24.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06454045 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of Platelet Aggregability in Patients With Previous Acute Myocardial Infarction or Concomitant Lower Extremity Peripheral Artery Disease

Typeobservational_patient_registrySponsorUniversity of Sao PauloRan2024 to 2028Enrolled100ConditionsCoronary Artery Disease, Peripheral Arterial DiseaseArmsClopidogrel
NCT06725875 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Effects of White Noise and Earplugs Applied During Coronary Angiography on Patients' Physiological Parameters, Pain, Comfort and Procedure Satisfaction: A Randomized Controlled Experimental Study

TypeinterventionalSponsorDi̇lek SoyluRan2024 to 2025Enrolled90ConditionsCoronary Angiography (CAG)ArmsWhite Noise Group, Earplug group
3 · Its place in the literature

Who cites it

208 citing papers in PubMed, 19 syntheses or guidelines pooled it, 434 citations in OpenAlex.

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148 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Rupert BauersachsDepartment of Vascular Medicine, Klinikum Darmstadt GmbH, Darmstadt, Germany.ORCID https://orcid.org/0000-0001-6192-1741
Uwe ZeymerKlinikum der Stadt Ludwigshafen, Medizinische Klinik B, Ludwigshafen am Rhein, Germany.
Jean-Baptiste BrièreBayer AG, Berlin, Germany.
Caroline MarreCreativ-Ceutical, Paris, France.
Kevin BowrinBayer PLC, Reading, UK.
Maria HuelsebeckBayer AG, Berlin, Germany.
Bayer (Germany) · DEBayer (United Kingdom) · GBCreativ-Ceutical (France) · FRJohannes Gutenberg University Mainz · DEKlinikum Ludwigshafen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtherothrombotic disease, including coronary artery disease (CAD) and peripheral artery disease (PAD), can lead to cardiovascular (CV) events, such as myocardial infarction, stroke, limb ischemia, heart failure, and CV death.

aimEvaluate the humanistic and economic burden of CAD and PAD and identify unmet needs through a comprehensive literature review.

methodsRelevant search terms were applied across online publication databases. Studies published between January 2010 and August 2017 meeting the inclusion/exclusion criteria were selected; guidelines were also included. Two rounds of screening were applied to select studies of relevance.

resultsWorldwide data showed approximately 5-8% prevalence of CAD and 10-20% prevalence of PAD, dependent on the study design, average age, gender, and geographical location. Data from the REACH registry indicated that 18-35% of patients with CAD and 46-68% of patients with PAD had disease in one or more vascular beds. Use of medication to control modifiable CV risk factors was variable by country (lower in France than in Canada); statins and aspirin were the most widely used therapies in patients with chronic disease. Survival rates have improved with medical advancements, but there is an additional need to improve the humanistic burden of disease (i.e., associated disability and quality of life). The economic burden of atherothrombotic disease is high and expected to increase with increased survival and the aging population.

conclusionCAD and PAD represent a substantial humanistic and economic burden worldwide, highlighting a need for new interventions to reduce the incidence of atherothrombotic disease.

Indexed as

Global HealthAgedCoronary Artery DiseaseCost of IllnessFemaleHealth Care CostsHealth Services Needs and DemandHumansIncidenceMalePeripheral Arterial DiseasePrevalencePrognosisRisk Factors

Identifiers

PMID32099582
PMCPMC7024142
OpenAlexW2990657953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.