Evidence map›Paper›PMID 32099543›Full record

ReviewAnesthesiology research and practice2020

Quo Vadis PCA? A Review on Current Concepts, Economic Considerations, Patient-Related Aspects, and Future Development with respect to Patient-Controlled Analgesia.

S Nardi-Hiebl, L H J Eberhart, M Gehling, T Koch, T Schlesinger, P Kranke

Registry-linked trialAbstract readReview
In one paragraph

Review in Anesthesiology research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06774274 (Analgesic Efficacy of Intravenous Ketamine as a Continuous Infusion vs PCA in the Management of Acute Postoperative Pain in Major Orthopedic Surgery), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06774274 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Analgesic Efficacy of Intravenous Ketamine as a Continuous Infusion vs PCA in the Management of Acute Postoperative Pain in Major Orthopedic Surgery: A Randomized Clinical Trial

TypeinterventionalSponsorUniversidad de AntioquiaRan2025 to 2027Enrolled120ConditionsPain, Postoperative, Opioid Use, Major SurgeryArmsKetamine infusion, PCA Ketamine
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Patient-controlled subcutaneous analgesia with hydromorphone in cancer pain management.Frontiers in pain research (Lausanne, Switzerland) · 2025
    Article
  4. Effect of Educational Tools on the use of Patient-Controlled Analgesia Devices.Turkish journal of anaesthesiology and reanimation · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S Nardi-HieblDepartment of Anesthesia and Intensive Care, University Hospital Marburg, Marburg, Germany.ORCID https://orcid.org/0000-0003-3563-3505
L H J EberhartDepartment of Anesthesia and Intensive Care, University Hospital Marburg, Marburg, Germany.
M GehlingDepartment of Anesthesia and Intensive Care, University Hospital Marburg, Marburg, Germany.
T KochDepartment of Anesthesia and Intensive Care, University Hospital Marburg, Marburg, Germany.
T SchlesingerDepartment of Anaesthesia and Critical Care, University Hospitals of Wuerzburg, Wuerzburg, Germany.
P KrankeDepartment of Anaesthesia and Critical Care, University Hospitals of Wuerzburg, Wuerzburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review assesses four interrelating aspects of patient-controlled analgesia (PCA), a long-standing and still widely used concept for postoperative pain management. Over the years, anaesthesiologists and patients have appreciated the benefits of PCA alike. The market has seen new technologies leveraging noninvasive routes of administration and, thus, further increasing patient and staff satisfaction as well as promoting safety aspects. Pharmaceutical research focuses on the reduction or avoidance of opioids, side effects, and adverse events although influence of these aspects appears to be minor. The importance of education is still eminent, and new educational formats are tested to train healthcare professionals and patients likewise. New PCA technology can support the implementation of efficient processes to reduce workload and human errors; however, these new products come with a cost, which is not necessarily reflected through beneficial budget impact or significant improvements in patient outcome. Although first steps have been taken to better recognize the importance of postoperative pain management through the introduction of value-based reimbursement, in most western countries, PCA is not specifically compensated. PCA is still an effective and valued technique for postoperative pain management. Although there is identifiable potential for future developments in various aspects, this potential has not materialized in new products.

Identifiers

PMID32099543
PMCPMC7040376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.