ArticleRisk management and healthcare policy2020
Drug Utilization Pattern of Antibiotics: The Role of Age, Sex and Municipalities in Determining Variation.
Article in Risk management and healthcare policy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Trial
- Mapping socioeconomic factors driving antimicrobial resistance in humans: An umbrella review.One health (Amsterdam, Netherlands) · 2025Review
- Rapid diagnostics to improve antibiotic prescribing in children: one piece of a much larger jigsaw.The Lancet regional health. Europe · 2025Article
- The European Drug-Drug Interaction (EuroDDI) Study Protocol: A Cross-Country Comparison of Drug-Drug Interaction Prevalence in the Older Community-Dwelling Population.Pharmacoepidemiology and drug safety · 2025Article
- Article
- Longitudinal Trajectory Modeling to Assess Adherence to Sacubitril/Valsartan among Patients with Heart Failure.Pharmaceutics · 2023Article
- Prevalence ofAntibiotics (Basel, Switzerland) · 2022Article
- Risk of SARS-CoV-2 Infection Breakthrough among the Non-Vaccinated and Vaccinated Population in Italy: A Real-World Evidence Study Based on Big Data.Healthcare (Basel, Switzerland) · 2022Article
- Antibiotic Prescribing Patterns in Paediatric Primary Care in Italy: Findings from 2012-2018.Antibiotics (Basel, Switzerland) · 2021Article
- Baseline Drug Treatments as Indicators of Increased Risk of COVID-19 Mortality in Spain and Italy.International journal of environmental research and public health · 2021Observational
- Pre-Exposure Prophylaxis with Hydroxychloroquine Does Not Prevent COVID-19 nor Virus Related Venous Thromboembolism.Viruses · 2021Article
- The Internet: Friend or Foe of Antibiotic Resistance? Results of a Cross-Sectional Study among Italian University Students.Antibiotics (Basel, Switzerland) · 2021Article
- Risk of Hospitalization for Adverse Drug Events in Women and Men: A Post Hoc Analysis of an Active Pharmacovigilance Study in Italian Emergency Departments.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Drug-utilisation profiles and COVID-19.Scientific reports · 2021Article
- Characteristics of patients infected with Clostridioides difficile at a Saudi Tertiary Academic Medical Center and assessment of antibiotic duration.Gut pathogens · 2021Article
- Article
- Rapid Increase of Oral Bacteria in Nasopharyngeal Microbiota After Antibiotic Treatment in Children With Invasive Pneumococcal Disease.Frontiers in cellular and infection microbiology · 2021Article
- Geographical Variation in Medication Prescriptions: A Multiregional Drug-Utilization Study.Frontiers in pharmacology · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose was to analyze drug prescription and antibiotic use by age and sex in Italy's Campania Region, and to estimate the distribution of prescription rates in children (≤14 years old), adults (between 15 and 65 years old), and older adults (≥65 years old) at a municipality level.
methodsThis was a retrospective analysis of pharmacy records in Campania (Southern Italy), in 2016. Difference in antibiotic prescriptions in different age groups was assessed by prevalence rates. Age-adjusted prevalence rates were categorized into quintiles and mapped by the patient's municipality of residence. Relationship between prevalence rates for the different age groups was estimated using the non-parametric Spearman rank correlation test.
resultsThere were 2,738,118 were patients with at least one antibiotic prescription. Antibiotics prescription was higher in children aged <5 years and in the older adults aged >70 years. Prevalence rate distribution was different among municipalities in all age groups. A positive correlation between the rank distribution of prevalence rates at municipality level was identified for children and adults (rs=0.56;
conclusionA considerably high use of antibiotic drugs has been detected in Campania Region, with values exceeding the regional and national average. Prescriptions at municipal level differ from one age group to another. Antibiotic use is often unjustified, and to decrease the number of prescriptions and improve their appropriateness, several measures at territorial level are recommended.
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