Evidence map›Paper›PMID 32099442›Full record

ArticlePharmacogenomics and personalized medicine2019

Elaine Chow, Emily Wm Poon, Benny Sp Fok, Juliana Cn Chan, Brian Tomlinson

Open access · goldAbstract read
In one paragraph

Article in Pharmacogenomics and personalized medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Elaine ChowPhase 1 Clinical Trial Centre, The Chinese University of Hong Kong, Hong Kong.ORCID 0000-0002-4147-3387
Emily Wm PoonDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong.
Benny Sp FokPhase 1 Clinical Trial Centre, The Chinese University of Hong Kong, Hong Kong.
Juliana Cn ChanDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong.ORCID 0000-0003-1325-1194
Brian TomlinsonPhase 1 Clinical Trial Centre, The Chinese University of Hong Kong, Hong Kong.ORCID 0000-0001-6717-5444
Chinese University of Hong Kong · HKMacau University of Science and Technology · MO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies suggest gliclazide is metabolised primarily by CYP2C19 rather than CYP2C9, unlike other sulphonylureas.

methodsWe investigated the effect of CYP2C19 polymorphisms on gliclazide pharmacokinetics in 15 healthy male Chinese subjects after a single 80mg oral dose.

resultsIn

conclusion

Indexed as

CYP2C19gliclazidepharmacogenetics

Identifiers

PMID32099442
PMCPMC6997415
OpenAlexW2997388069

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.