ArticleNeuropsychiatric disease and treatment2020
Family-Based Analysis Combined with Case-Controls Study Implicate Roles of PCNT in Tourette Syndrome.
Article in Neuropsychiatric disease and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 citing papers in PubMed, 4 citations in OpenAlex.
- ASH1L may contribute to the risk of Tourette syndrome: Combination of family-based analysis and case-control study.Brain and behavior · 2022Article
- Article
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Authors and funding
10 authors at 6 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveTourette syndrome (TS) is a childhood-onset neuro-developmental disorder and the genetic factors play an important role in its etiology. As pericentrin (PCNT) binds to disruption-in-schizophrenia 1 (DISC1) and is a risk factor for many mental illnesses, we aimed to investigate the effect of PCNT on TS in the Chinese Han population.
methodsFive tag single nucleotide polymorphisms (SNPs) (rs17371795, rs2839227, rs2839228, rs6518291 and rs9983522) in
resultsThe allele frequencies revealed a significant difference of rs17371795, rs2839227 and rs2839228 between TS patients and controls (for rs17371795:
conclusionOur study suggested genetic variability at the PCNT locus may be associated with TS risk in the Chinese Han population.
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