Evidence map›Paper›PMID 32099352›Full record

ReviewInternational journal of nanomedicine2019

Recent Progress of Nanoscale Metal-Organic Frameworks in Cancer Theranostics and the Challenges of Their Clinical Application.

Wenjie Sun, Shuying Li, Guiliang Tang, Yuan Luo, Shijing Ma, Shaoxing Sun, Jiangbo Ren, Yan Gong, Conghua Xie

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Recent nanotheranostic approaches in cancer research.Clinical and experimental medicine · 2024
    Review
  5. Review
  6. Review
  7. Review
  8. High-Z Metal-Organic Frameworks for X-ray Radiation-Based Cancer Theranostics.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Wenjie SunDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Shuying LiDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Guiliang TangDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Yuan LuoDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Shijing MaDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Shaoxing SunDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Jiangbo RenDepartment of Biological Repositories, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.ORCID 0000-0002-9924-7032
Yan GongDepartment of Biological Repositories, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.ORCID 0000-0002-4805-0459
Conghua XieDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.ORCID 0000-0001-6623-9864
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing incidence of cancer raises an urgent need to develop effective diagnostic and therapeutic strategies. With the rapid development of nanomedicine, nanoscale metal-organic frameworks (NMOFs) presented promising potential in various biomedical applications in the last 2 decades, especially in cancer theranostics. Due to the unique features of NMOFs, including structural diversities, enormous porosity, multifunctionality and biocompatibility, they have been widely used to deliver imaging contrast agents and therapeutic drugs. Moreover, multiple types of contrast agents, anti-cancer drugs and targeting ligands could be co-delivered through one single NMOF to enable combination therapy. Co-delivering system using NMOFs helped to avoid multidrug resistance, to reduce adverse effects, to achieve imaging-guided precise therapy and to enhance anti-cancer efficacy. This review summarized the recent research advances on the application of NMOFs in biomedical imaging and cancer treatments in the last few years. The current challenges that impeding their translation to clinical practices and the perspectives for their future applications were also highlighted and discussed.

Indexed as

AnimalsAntineoplastic AgentsCombined Modality TherapyContrast MediaDrug Delivery SystemsHumansMetal-Organic FrameworksNanomedicineNeoplasmsTheranostic NanomedicineAntineoplastic AgentsContrast MediaMetal-Organic Frameworksbiomedical imagingclinical translationcombination therapynanomedicinetheranostic platform

Identifiers

PMID32099352
PMCPMC6997222
OpenAlexW2996868053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.