Evidence map›Paper›PMID 32098943›Full record

ArticleThe American journal of case reports2020

Successful Extracorporeal Membrane Oxygenation Treatment in an Acquired Immune Deficiency Syndrome (AIDS) Patient with Acute Respiratory Distress Syndrome (ARDS) Complicating Pneumocystis jirovecii Pneumonia: A Challenging Case.

Benedetto Maurizio Celesia, Andrea Marino, Savino Borracino, Antonio F Arcadipane, Grazia Pantò, Maria Gussio, Salvatore Coniglio, Alfio Pennisi, Bruno Cacopardo, Giovanna Panarello

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Critical Care Pharmacology of Antiretroviral Therapy in Adults.European journal of drug metabolism and pharmacokinetics · 2025
    Review
  2. Article
  3. Navigating the Nexus: HIV and Breast Cancer-A Critical Review.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Infectious disease reports · 2022
    Article
  11. Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Benedetto Maurizio CelesiaInfectious Diseases Unit, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy.
Andrea MarinoInfectious Diseases Unit, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy.
Savino BorracinoIntensive Care Unit, ARNAS Garibaldi Hospital, Catania, Italy.
Antonio F ArcadipaneIntensive Care Unit, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo, Italy.
Grazia PantòInfectious Diseases Unit, Cannizzaro Hospital, Catania, Italy.
Maria GussioInfectious Diseases Unit, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy.
Salvatore ConiglioIntensive Care Unit, ARNAS Garibaldi Hospital, Catania, Italy.
Alfio PennisiNeurologic and Respiratory Rehabilitation Unit, Casa di Cura "Mons. G. Calaciura", Biancavilla, Italy.
Bruno CacopardoInfectious Diseases Unit, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy.
Giovanna PanarelloIntensive Care Unit, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo, Italy.
Ospedale Garibaldi · ITIstituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione · ITCasa di Cura Villa Bianca · ITOspedale Cannizzaro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Patients with HIV infection tend to have poor intensive care unit (ICU) outcomes; however, survival in the modern combination antiretroviral therapy (cART) era has markedly improved, but Pneumocystis jirovecii pneumonia (PJP) still remains a preeminent cause of respiratory failure in AIDS patients. Extracorporeal membrane oxygenation (ECMO) is an adapted cardiopulmonary bypass circuit for temporary life support for patients not responding to conventional treatment. CASE REPORT A 43-year-old male HIV "late presenter" was admitted to our hospital for fever and dyspnea. A chest CT scan revealed bilateral ground-glass opacities. Empiric antibiotic treatment and cART were started. The emergence of ARDS due to PJP dictated urgent veno-venous (VV) ECMO placement. One week later, radiologic findings and respiratory function had improved and the patient was started on a weaning trial from ECMO and removed 12 days after placement. CONCLUSIONS Acute respiratory distress syndrome (ARDS) is a potentially reversible clinical syndrome with a high mortality rate. ECMO is a rescue therapy allowing lung recovery during acute processes and should be considered an adequate treatment option in HIV+ patients with respiratory failure. ECMO should be considered a useful and adequate treatment option in AIDS patients who have a high risk of dying from respiratory failure.

Indexed as

Extracorporeal Membrane OxygenationAcquired Immunodeficiency SyndromeAdultAIDS-Related Opportunistic InfectionsHumansImmunocompromised HostMalePneumocystis cariniiPneumonia, PneumocystisRespiratory Distress Syndrome

Identifiers

PMID32098943
PMCPMC7061932
OpenAlexW3001500402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.