ArticlemBio2020
SpoT Induces Intracellular
Open access · goldAbstract read
In one paragraph
Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 24 citations in OpenAlex.
- Stress-induced iron-sulfur cluster damage as a conserved trigger of the bacterial stringent response.Nature communications · 2026Article
- Disruption of sulfur transferase complex increases bacterial intramacrophage persistence.PLoS pathogens · 2025Article
- Ecotin protects Salmonella Typhimurium against the microbicidal activity of host proteases.PLoS pathogens · 2025Article
- Mechanisms of antibiofilm compounds JG-1 and M4 across multiple species: alterations of protein interactions essential to biofilm formation.Frontiers in cellular and infection microbiology · 2025Article
- Evolution of Resistance against Ciprofloxacin, Tobramycin, and Trimethoprim/Sulfamethoxazole in the Environmental Opportunistic PathogenAntibiotics (Basel, Switzerland) · 2024Article
- Phosphorus starvation response and PhoB-independent utilization of organic phosphate sources byMicrobiology spectrum · 2023Article
- Structure of SpoT reveals evolutionary tuning of catalysis via conformational constraint.Nature chemical biology · 2023Article
- In vitro Activity of Cefepime/Avibactam Against Carbapenem ResistantInfection and drug resistance · 2023Article
- Article
- Manganese Utilization inFrontiers in cell and developmental biology · 2022Review
- Article
- Emerging and divergent roles of pyrophosphorylated nucleotides in bacterial physiology and pathogenesis.PLoS pathogens · 2021Review
- The stringent response and physiological roles of (pp)pGpp in bacteria.Nature reviews. Microbiology · 2021Review
- Salmonella enters a dormant state within human epithelial cells for persistent infection.PLoS pathogens · 2021Article
- Impact of the Resistance Responses to Stress Conditions Encountered in Food and Food Processing Environments on the Virulence and Growth Fitness of Non-TyphoidalFoods (Basel, Switzerland) · 2021Review
- (p)ppGpp-Dependent Regulation of the Nucleotide Hydrolase PpnN Confers Complement Resistance in Salmonella enterica Serovar Typhimurium.Infection and immunity · 2021Article
- The secondary messenger ppGpp interferes with cAMP-CRP regulon by promoting CRP acetylation in Escherichia coli.PloS one · 2021Article
- Survival of the Fittest: The Relationship of (p)ppGpp With Bacterial Virulence.Frontiers in microbiology · 2020Review
- Possible Roles for Basal Levels of (p)ppGpp: Growth Efficiency Vs. Surviving Stress.Frontiers in microbiology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Liam F FitzsimmonsUniversity of Colorado School of Medicine, Department of Immunology and Microbiology, Aurora, Colorado, USA.
Lin LiuUniversity of Colorado School of Medicine, Department of Immunology and Microbiology, Aurora, Colorado, USA.
Sashi KantUniversity of Colorado School of Medicine, Department of Immunology and Microbiology, Aurora, Colorado, USA.
Ju-Sim KimUniversity of Colorado School of Medicine, Department of Immunology and Microbiology, Aurora, Colorado, USA.
James K TillUniversity of Colorado School of Medicine, Department of Immunology and Microbiology, Aurora, Colorado, USA.
Jessica Jones-CarsonUniversity of Colorado School of Medicine, Department of Immunology and Microbiology, Aurora, Colorado, USA.
Steffen PorwollikUniversity of California Irvine, School of Medicine, Department of Microbiology and Molecular Genetics, Irvine, California, USA.
Michael McClellandUniversity of California Irvine, School of Medicine, Department of Microbiology and Molecular Genetics, Irvine, California, USA.
Andres Vazquez-TorresUniversity of Colorado School of Medicine, Department of Immunology and Microbiology, Aurora, Colorado, USA Andres.Vazquez-Torres@cuanschutz.edu.
University of Colorado Denver · USUniversity of California, Irvine · US
Funding
Salmonella evasion of NADPH oxidase-dependent killingR01AI054959 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAZQUEZ-TORRES, ANDRES · 2003 to 2018
$5.2MMolecular determinants of oxidative stress in Salmonella pathogenesisR01AI136520 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Andres Vazquez-Torres · 2018 to 2026
$3.7MMolecular Pathogenesis of Infectious DiseasesT32AI052066 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAN DYK, LINDA F. · 2002 to 2022
$2.3MAnalysis of intracellular host defenses in Salmonella pathogenesisR56AI054959 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAZQUEZ-TORRES, ANDRES · 2008 to 2008
$378kBarcoding a Salmonella gene knockout libraryR03AI139557 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI MCCLELLAND, MICHAEL · 2019 to 2020
$157kRegulation of Nucleotide Pools Mediates Recovery from Nitric Oxide-Induced Cytotoxicity in SalmonellaF31AI118223 · NIAID · UNIVERSITY OF COLORADO DENVER · PI FITZSIMMONS, LIAM FRY · 2016 to 2017
$62kIRON STORAGE PROTEINS AND SALMONELLA PATHOGENESISF32AI010181 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAZQUEZ-TORRES, ANDRES · 1998 to 2000
$46kMolecular Analysis of Bacterial Adaptive Response to Host Reactive SpeciesI01BX002073 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI Andres Vazquez-Torres · 2013 to 2026
–BLRD VA I01 BX002073NIAID NIH HHS F31 AI118223NIAID NIH HHS F32 AI010181NIAID NIH HHS R01 AI054959NIAID NIH HHS R01 AI136520NIAID NIH HHS R03 AI139557NIAID NIH HHS R56 AI054959NIAID NIH HHS T32 AI052066
Abstract
Guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), together named (p)ppGpp, regulate diverse aspects of
Indexed as
AnimalsBacterial ProteinsCell SurvivalDisease Models, AnimalGram-Negative BacteriaGram-Positive BacteriaGuanosine PentaphosphateGuanosine TetraphosphateImmunity, InnateLigasesMicePhagosomesPyrophosphatasesSalmonellaTranscription Factor RelAVirulenceBacterial Proteinsguanosine 3',5'-polyphosphate synthetasesGuanosine PentaphosphateGuanosine TetraphosphateLigasesPyrophosphatasesRela protein, mouseTranscription Factor RelAbacterial pathogenesisgeneticsinnate immunitymacrophagesSalmonellastringent responsetransposons
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.