Evidence map›Paper›PMID 32098822›Full record

ArticlemBio2020

HIV Drugs Inhibit Transfer of Plasmids Carrying Extended-Spectrum β-Lactamase and Carbapenemase Genes.

Michelle M C Buckner, M Laura Ciusa, Richard W Meek, Alice R Moorey, Gregory E McCallum, Emma L Prentice, Jeremy P Reid, Luke J Alderwick, Alessandro Di Maio, Laura J V Piddock

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

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  15. Characterizations ofFrontiers in microbiology · 2023
    Article
  16. Review
  17. Article
  18. New perspectives on mobile genetic elements: a paradigm shift for managing the antibiotic resistance crisis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Michelle M C BucknerInstitute of Microbiology & Infection, College of Medical & Dental Sciences, University of Birmingham, Edgbaston, United Kingdom m.buckner@bham.ac.uk.ORCID 0000-0001-9884-2318
M Laura CiusaInstitute of Microbiology & Infection, College of Medical & Dental Sciences, University of Birmingham, Edgbaston, United Kingdom.
Richard W MeekInstitute of Microbiology & Infection, College of Medical & Dental Sciences, University of Birmingham, Edgbaston, United Kingdom.
Alice R MooreyInstitute of Microbiology & Infection, College of Medical & Dental Sciences, University of Birmingham, Edgbaston, United Kingdom.
Gregory E McCallumInstitute of Microbiology & Infection, College of Medical & Dental Sciences, University of Birmingham, Edgbaston, United Kingdom.
Emma L PrenticeInstitute of Microbiology & Infection, College of Medical & Dental Sciences, University of Birmingham, Edgbaston, United Kingdom.
Jeremy P ReidInstitute of Microbiology & Infection, College of Medical & Dental Sciences, University of Birmingham, Edgbaston, United Kingdom.
Luke J AlderwickInstitute of Microbiology & Infection, School of Biosciences, University of Birmingham, Edgbaston, United Kingdom.
Alessandro Di MaioBirmingham Advanced Light Microscopy, School of Biosciences, University of Birmingham, Edgbaston, United Kingdom.
Laura J V PiddockInstitute of Microbiology & Infection, College of Medical & Dental Sciences, University of Birmingham, Edgbaston, United Kingdom.ORCID 0000-0003-1460-473X
University of Birmingham · GB

Funding

Medical Research Council MR/N012933/1Wellcome Trust
6 · The paper itself

Abstract

Antimicrobial-resistant (AMR) infections pose a serious risk to human and animal health. A major factor contributing to this global crisis is the sharing of resistance genes between different bacteria via plasmids. The WHO lists

Indexed as

AbacavirAnti-Bacterial AgentsAnti-HIV AgentsBacterial Proteinsbeta-LactamasesDideoxynucleosidesDrug Resistance, BacterialEnterobacteriaceaeEscherichia coliGene Transfer, HorizontalHIV InfectionsHIV Integrase InhibitorsKlebsiella pneumoniaePlasmidsZidovudineAbacavirAnti-Bacterial AgentsAnti-HIV AgentsBacterial Proteinsbeta-LactamasescarbapenemaseDideoxynucleosidesHIV Integrase InhibitorsZidovudineantimicrobial resistancecarbapenemasecarbapenemasesCTX-ME. coliESBLKPCK. pneumoniae

Identifiers

PMID32098822
PMCPMC7042701
OpenAlexW3007211193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.