Evidence map›Paper›PMID 32098719›Full record

ArticleBrazilian journal of otorhinolaryngology

Nuocytes from mesenteric lymph node promote allergic responses in a mouse model.

Lin Lin, Xinyue Tang, Zheng Chen, Jinjin Wei, Fei Dai, Guangbin Sun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lin LinHuashan Hospital of Fudan University, Department of Otorhinolaryngology-Head and Neck Surgery, Shanghai, China. Electronic address: linlinhsn@aliyun.com.
Xinyue TangHuashan Hospital North of Fudan University, Department of Otorhinolaryngology-Head and Neck Surgery, Shanghai, China.
Zheng ChenHuashan Hospital North of Fudan University, Department of Otorhinolaryngology-Head and Neck Surgery, Shanghai, China.
Jinjin WeiHuashan Hospital North of Fudan University, Department of Otorhinolaryngology-Head and Neck Surgery, Shanghai, China.
Fei DaiHuashan Hospital North of Fudan University, Department of Otorhinolaryngology-Head and Neck Surgery, Shanghai, China.
Guangbin SunHuashan Hospital of Fudan University, Department of Otorhinolaryngology-Head and Neck Surgery, Shanghai, China.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNuocytes play an important role in Type 2 immunity. However, the contribution of ILC2s to allergic rhinitis remains to be clearly elucidated.

objectiveTo evaluate the role of nuocytes from mesenteric lymph node on allergic responses in mice.

methodsAfter intraperitoneal administration of interleukin IL-25 and IL-33 to wild-type and Il17br

resultsWe showed that nuocytes in the mesenteric lymph nodes of wild-type mice were upregulated after application of IL-25 and IL-33, and were induced to produce IL-5 and IL-13. Numbers of sneezing and nasal rubbing as well as eosinophils were all enhanced after the adoptive transfer of wild-type nuocytes. Concentrations of IL-5, IL-13, IL-25 and IL-33 in nasal lavage fluid of allergic mice were also increased. However, nuocytes fromIl17br

conclusionThe findings demonstrate that nuocytes from the mesenteric lymph nodes of wild-type mice promote allergic responses in a mouse model.

Indexed as

Immunity, InnateRhinitis, AllergicAnimalsCytokinesDisease Models, AnimalInterleukin-1 Receptor-Like 1 ProteinLymph NodesLymphocytesMiceNasal MucosaCytokinesIl1rl1 protein, mouseInterleukin-1 Receptor-Like 1 ProteinAllergic rhinitisAnimal modelsLymph nodeLymphoid cellsMice

Identifiers

PMID32098719
PMCPMC9422417
OpenAlexW3006602753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.