Observational studyJournal of the American Heart Association2020
Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident Dyslipidemia in US Adults: The Framingham Heart Study.
Observational study in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Comprehensive review of carbonated soft drink consumption rates and their public health importance.BMC public health · 2026Pooled it
- Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations.Circulation. Genomic and precision medicine · 2021Trial
- Effects of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Beverages on Cardiometabolic Risk Factors, Body Composition, and Sweet Taste Preference: A Randomized Controlled Trial.Journal of the American Heart Association · 2020Trial
- Proteomic signatures of sweetened beverages are associated with higher risk of adverse liver outcomes.Nature food · 2025Article
- Mediterranean diet, metabolic signature, genetic predisposition, and risk of rheumatoid arthritis: a large-scale population-based prospective cohort study.The American journal of clinical nutrition · 2025Article
- Evaluating sugar-sweetened beverage tax effects: online price and sales data from grocers in Canada.Health promotion international · 2025Article
- Impact of carbohydrate quality on the association between low-carbohydrate diet scores and longitudinal changes of cardiometabolic risk factors.Nutrition journal · 2025Article
- Fact sheet: nationwide trends in dietary intakes among Korean adults, 2013-2022.The Korean journal of internal medicine · 2025Article
- Longitudinal associations between dietary diversity and serum lipid markers in Japanese workers.European journal of clinical nutrition · 2025Article
- Reduced rank regression dietary patterns and dyslipidemia in Brazilian adolescents: results from the Study of Cardiovascular Risk in Adolescents (ERICA).European journal of clinical nutrition · 2025Article
- The association of dietary pattern with the risk of common chronic diseases in Shandong Province, China: a cross-sectional study.Frontiers in public health · 2025Article
- Associations between dietary diversity and dyslipidemia among Japanese workers: cross-sectional study and longitudinal study findings.European journal of nutrition · 2024Article
- 2024 KSoLA consensus on secondary dyslipidemia.The Korean journal of internal medicine · 2024Review
- 2024 KSoLA Consensus on Secondary Dyslipidemia.Journal of lipid and atherosclerosis · 2024Review
- Metabolite Profiles of Plant-Based Diets and Cardiometabolic Risk in the Mediators of Atherosclerosis in South Asians Living in America Study.The Journal of nutrition · 2024Article
- From plate to profile: investigating the influence of dietary habits and inactive lifestyle on lipid profile in medical students at clerkship.BMC nutrition · 2024Article
- Prevalence of dyslipidemia and associated factors in sedentary occupational population from Shanghai: a cross-sectional study.Archives of public health = Archives belges de sante publique · 2024Article
- Associations between the Genetic Heritability of Dyslipidemia and Dietary Patterns in Korean Adults Based on Sex Differences.Nutrients · 2023Article
- Association of Urinary Zinc Concentrations with Dyslipidemia and Its Subtypes: Baseline Data from the Chinese Multi-Ethnic Cohort (CMEC) Study.Biological trace element research · 2023Article
- Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
Background Limited data are available on the prospective relationship between beverage consumption and plasma lipid and lipoprotein concentrations. Two major sources of sugar in the US diet are sugar-sweetened beverages (SSBs) and 100% fruit juices. Low-calorie sweetened beverages are common replacements. Methods and Results Fasting plasma lipoprotein concentrations were measured in the FOS (Framingham Offspring Study) (1991-2014; N=3146) and Generation Three (2002-2001; N=3584) cohorts. Beverage intakes were estimated from food frequency questionnaires and grouped into 5 intake categories. Mixed-effect linear regression models were used to examine 4-year changes in lipoprotein measures, and Cox proportional hazard models were used to estimate hazard ratios for incident dyslipidemia, adjusting for potential confounding factors. We found that regular (>1 serving per day) versus low (<1 serving per month) SSB consumption was associated with a greater mean decrease in high-density lipoprotein cholesterol (β±standard error -1.6±0.4 mg/dL;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.