Evidence map›Paper›PMID 32098599›Full record

ArticleJournal of the American Heart Association2020

Impact of Different Electronic Cohort Definitions to Identify Patients With Atrial Fibrillation From the Electronic Medical Record.

Rashmee U Shah, Rebeka Mukherjee, Yue Zhang, Aubrey E Jones, Jennifer Springer, Ian Hackett, Benjamin A Steinberg, Donald M Lloyd-Jones, Wendy W Chapman

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Electrocardiographic Predictors of Atrial Fibrillation.Medical sciences (Basel, Switzerland) · 2023
    Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Article
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  9. Article
  10. Complex Percutaneous Coronary Intervention Outcomes in Older Adults.Journal of the American Heart Association · 2023
    Article
  11. An introduction to ICD code development for pediatric neurology.Annals of the Child Neurology Society · 2023
    Review
  12. Article
  13. Artificial Intelligence Technologies in Cardiology.Journal of cardiovascular development and disease · 2023
    Review
  14. Article
  15. Article
  16. Article
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rashmee U ShahDivision of Cardiovascular Medicine Department of Internal Medicine University of Utah School of Medicine Salt Lake City UT.
Rebeka MukherjeeDivision of Cardiovascular Medicine Department of Internal Medicine University of Utah School of Medicine Salt Lake City UT.
Yue ZhangDivision of Epidemiology Department of Internal Medicine University of Utah School of Medicine Salt Lake City UT.
Aubrey E JonesDepartment of Population Health University of Utah School of Medicine Salt Lake City UT.
Jennifer SpringerDivision of Cardiovascular Medicine Department of Internal Medicine University of Utah School of Medicine Salt Lake City UT.
Ian HackettSection of Cardiology Department of Internal Medicine University of Chicago Pritzker School of Medicine Chicago IL.
Benjamin A SteinbergDivision of Cardiovascular Medicine Department of Internal Medicine University of Utah School of Medicine Salt Lake City UT.
Donald M Lloyd-JonesDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Wendy W ChapmanCentre for Digital Transformation of Health Victorian Comprehensive Cancer Centre Melbourne Australia.

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
Optimizing Outcomes for Patients with Heart Failure and Atrial FibrillationK23HL143156 · NHLBI · UNIVERSITY OF UTAH · PI STEINBERG, BENJAMIN ADAM · 2018 to 2022
$951k
Improving Cardiovascular Drug Safety With Automated Bleeding ClassificationK08HL136850 · NHLBI · UNIVERSITY OF UTAH · PI SHAH, RASHMEE U. · 2017 to 2020
$652k
NCATS NIH HHS UL1 TR002538NHLBI NIH HHS K08 HL136850NHLBI NIH HHS K23 HL143156
6 · The paper itself

Abstract

Background Electronic medical records (EMRs) allow identification of disease-specific patient populations, but varying electronic cohort definitions could result in different populations. We compared the characteristics of an electronic medical record-derived atrial fibrillation (AF) patient population using 5 different electronic cohort definitions. Methods and Results Adult patients with at least 1 AF billing code from January 1, 2010, to December 31, 2017, were included. Based on different electronic cohort definitions, we trained 5 different logistic regression models using a labeled training data set (n=786). Each model yielded a predicted probability; patients were classified as having AF if the probability was higher than a specified cut point. Test characteristics were calculated for each model. These models were then applied to the full cohort and resulting characteristics were compared. In the training set, the comprehensive model (including demographics, billing codes, and natural language processing results) performed best, with an area under the curve of 0.89, sensitivity of 0.90, and specificity of 0.87. Among a candidate population (n=22 000), the proportion of patients identified as having AF varied from 61% in the model using diagnosis or procedure

Indexed as

Electronic Health RecordsAdultAgedAnticoagulantsAtrial FibrillationCohort StudiesCurrent Procedural TerminologyElectrocardiographyFemaleHumansInternational Classification of DiseasesLogistic ModelsMaleMiddle AgedNatural Language ProcessingSensitivity and SpecificityAnticoagulantsatrial fibrillationelectronic health recordshealth services researchinformaticsquality of care

Identifiers

PMID32098599
PMCPMC7335556

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.